From: Evidence review for coordinating care
Copyright © NICE 2018.
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National Guideline Centre (UK). Evidence review for coordinating care: Renal replacement therapy and conservative management: Evidence review. London: National Institute for Health and Care Excellence (NICE); 2018 Oct. (NICE Guideline, No. 107.)
Evidence review for coordinating care: Renal replacement therapy and conservative management: Evidence review.
Show detailsTable 3Clinical evidence summary: Key worker vs usual care
| Outcomes | No of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with Usual care | Risk difference with Key worker (95% CI) | ||||
| Symptoms (KDQOL symptom/problem, 0–100, high is better) |
220 (2 studies) 12 weeks |
due to risk of bias, imprecision |
The mean symptoms in the control groups was 66.5 |
The mean symptoms in the intervention groups was 3.62 higher (0.27 to 6.97 higher) | |
| Functional measures (KDQOL burden of kidney disease, 0–100, high is better) |
220 (2 studies) 12 weeks |
MODERATE1 due to risk of bias |
The mean functional measures in the control groups was 21.5 |
The mean functional measures in the intervention groups was 0.72 higher (2.97 lower to 4.42 higher) | |
| Rate of readmission |
135 (1 study) 12 weeks |
due to risk of bias, imprecision |
Rate Ratio 0.57 (0.21 to 1.58) | Moderate | |
| 150 per 1000 |
65 fewer per 1000 (from 119 fewer to 87 more) | ||||
| Rate of clinic visits |
135 (1 study) 12 weeks |
due to risk of bias, imprecision |
Rate Ratio 0.53 (0.34 to 0.82) | Moderate | |
| 880 per 1000 |
414 fewer per 1000 (from 158 fewer to 581 fewer) | ||||
| Mental wellbeing (KDQOL emotional wellbeing, 0–100, high is better) |
220 (2 studies) 12 weeks |
MODERATE1 due to risk of bias |
The mean mental wellbeing in the control groups was 63.4 |
The mean mental wellbeing in the intervention groups was 1.49 higher (3.59 lower to 6.57 higher) | |
| Experience of care (KDQOL patient satisfaction, 0–100, high is better) |
220 (2 studies) 12 weeks |
due to risk of bias, imprecision |
The mean experience of care in the control groups was 63.0 |
The mean experience of care in the intervention groups was 6.17 higher (2.33 to 10.01 higher) | |
- 1
Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias
- 2
Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs
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- Table 3, Clinical evidence summary: Key worker vs usual care - Evidence review f...Table 3, Clinical evidence summary: Key worker vs usual care - Evidence review for coordinating care
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