Closing Evidence Gaps in Clinical Prevention, a new consensus study report from the National Academies of Sciences, Engineering, and Medicine's Board on Population Health and Public Health Practice, evaluates evidence gaps in clinical prevention recommendations described by the United States Preventive Services Task Force and other clinical practice guideline developers and presents a taxonomy of these evidence gaps for future use. This report aims to improve the coordination of efforts to describe and communicate priority evidence gaps among funders and researchers. It also proposes new opportunities for collaboration among researchers, funders, and guideline developers to accelerate research that could close evidence gaps. The authoring committee has also developed an interactive graphic that can be used as a workflow diagram for implementing the taxonomy. This workflow walks users through reviewing evidence, characterizing evidence gaps using relevant taxonomies, and developing a research agenda. Click here to view and engage with the interactive graphic.

Contents

• The National Academies of SCIENCES • ENGINEERING • MEDICINE
• COMMITTEE ON ADDRESSING EVIDENCE GAPS IN CLINICAL PREVENTION RECOMMENDATIONS
• Reviewers
• Preface
• Acronyms and Abbreviations
• Summary
  • STATEMENT OF TASK
  • TAXONOMY
  • RECOMMENDATIONS
  • COMMITTEE VISION
  • REFERENCES
• 1. Introduction
  • STATEMENT OF TASK
  • COMMITTEE PROCESS
  • ORGANIZATION OF THE REPORT
  • REFERENCES
• 2. Clinical Practice Guidelines and the U.S. Preventive Services Task Force
  • WHAT ARE CLINICAL PRACTICE GUIDELINES?
  • U.S. PREVENTIVE SERVICES TASK FORCE
  • HOW OTHER CLINICAL PRACTICE GUIDELINE DEVELOPERS ADDRESS EVIDENCE GAPS
  • REFERENCES
• 3. Clinical Prevention Research Enterprise
  • NATIONAL INSTITUTES OF HEALTH
  • OTHER CLINICAL PREVENTION RESEARCH FUNDERS
  • RESEARCHERS
  • REFERENCES
• 4. Taxonomy and Workflow
  • COMMITTEE’S APPROACH
  • WORKFLOW
  • TAXONOMY FOR CLASSIFYING EVIDENCE GAPS
  • TAXONOMY FOR DEVELOPING THE RESEARCH AGENDA
  • EXAMPLES OF APPLYING THE TAXONOMY TO I STATEMENTS
  • REFERENCES
• 5. Recommendations
  • USING THE TAXONOMY
  • FOSTERING CLINICAL PREVENTION RESEARCH
  • ADVANCING THE WORK OF THE U.S. PREVENTIVE SERVICES TASK FORCE
  • COMMITTEE VISION
  • REFERENCES
• A. Topics with “I Statements” from the U.S. Preventive Services Task Force
• B. Research Methods
• C. Public Meeting Agendas
• D. Committee Member and Staff Biographies
• E. U.S. Preventive Services Task Force’s Reports to Congress
• F. U.S. Preventive Service Task Force Research Needs Statements from I Statements Issued Between 2017 and 2021

Suggested citation:

National Academies of Sciences, Engineering, and Medicine. 2022. Closing evidence gaps in clinical prevention. Washington, DC: The National Academies Press. https://doi.org/10.17226/26351.

Digital Object Identifier: https://doi.org/10.17226/26351 Library of Congress Catalog Number: 2021951344

Additional copies of this publication are available from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.

Printed in the United States of America