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Pluta R, editor. Cerebral Ischemia [Internet]. Brisbane (AU): Exon Publications; 2021 Nov 6. doi: 10.36255/exonpublications.cerebralischemia.2021.therapy

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Cerebral Ischemia [Internet].

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Figure 2. An overview of the different immune cells involved in the pathology of stroke.

Figure 2

An overview of the different immune cells involved in the pathology of stroke. Neurons, astrocytes and endothelial cells release danger-associated molecular patterns (DAMPs) after stroke. DAMPs activate microglia and peripheral immune cells such as T cells and B cells, yielding a proinflammatory cytokine secretion profile from these cells. Meanwhile M2 microglia, regulatory T cells (Treg) and regulatory B cells (Breg) release antiinflammatory mediators that help reduce neuroinflammation. However, the dual role of inflammation after ischemic stroke is still unclear.

From: Chapter 11, Treating Cerebral Ischemia: Novel Therapeutic Strategies from Experimental Stroke Research

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The authors confirm that the materials included in this chapter do not violate copyright laws. Where relevant, appropriate permissions have been obtained from the original copyright holder(s), and all original sources have been appropriately acknowledged or referenced.

Licence: This open access article is licenced under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/

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