From: When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome
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National Guideline Centre (UK). When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome: Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s: Evidence review A. London: National Institute for Health and Care Excellence (NICE); 2021 Aug. (NICE Guideline, No. 202.)
When to suspect OSAHS, OHS and COPD–OSAHS overlap syndrome: Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s: Evidence review A.
Show detailsTable 8Clinical evidence summary: People with type I diabetes vs control
| Outcomes | No of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with Control | Risk difference with Type I diabetes (95% CI) | ||||
| Increased risk of OSA |
198 (1 study) |
⊕⊝⊝⊝ VERY LOW1 due to risk of bias |
RR 3.4 (1.31 to 8.86) | Moderate | |
| 51 per 1000 |
122 more per 1000 (from 16 more to 401 more)2 | ||||
- 1
Risk of bias was assessed using the QUIPS checklist. Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias
- 2
GC considered the clinical importance of the effect estimate for each analysis on a case by case basis, taking into consideration the increment of the risk factor and the outcome under study.
- Review Obstructive sleep apnea/hypopnea syndrome.[Panminerva Med. 2013]Review Obstructive sleep apnea/hypopnea syndrome.De Backer W. Panminerva Med. 2013 Jun; 55(2):191-5.
- Review Positive airway pressure therapy variants for OSAHS, OHS and COPD–OSAHS overlap syndrome: Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s: Evidence review F[ 2021]Review Positive airway pressure therapy variants for OSAHS, OHS and COPD–OSAHS overlap syndrome: Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s: Evidence review FNational Guideline Centre (UK). 2021 Aug
- Review Obstructive sleep apnoea/hypopnoea syndrome in adults with Down syndrome.[Breathe (Sheff). 2016]Review Obstructive sleep apnoea/hypopnoea syndrome in adults with Down syndrome.Hill EA. Breathe (Sheff). 2016 Dec; 12(4):e91-e96.
- Sleep-disordered breathing in C57BL/6J mice with diet-induced obesity.[Sleep. 2018]Sleep-disordered breathing in C57BL/6J mice with diet-induced obesity.Fleury Curado T, Pho H, Berger S, Caballero-Eraso C, Shin MK, Sennes LU, Pham L, Schwartz AR, Polotsky VY. Sleep. 2018 Aug 1; 41(8).
- Objective and Subjective Prevalence of Obstructive Sleep Apnoea/Hypopnoea Syndrome in UK Adults with Down Syndrome: A Strong Marker for Diurnal Behavioural Disturbances.[Brain Sci. 2021]Objective and Subjective Prevalence of Obstructive Sleep Apnoea/Hypopnoea Syndrome in UK Adults with Down Syndrome: A Strong Marker for Diurnal Behavioural Disturbances.Hill EA, Williams LJ, Cooper SA, Riha RL. Brain Sci. 2021 Aug 31; 11(9). Epub 2021 Aug 31.
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