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National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Food and Nutrition Board; Committee on Scanning for New Evidence on Riboflavin to Support a Dietary Reference Intake Review; Vorosmarti A, Yaktine AL, Schneeman BO, editors. Scanning for New Evidence on Riboflavin to Support a Dietary Reference Intake Review. Washington (DC): National Academies Press (US); 2021 Jul 28.
Scanning for New Evidence on Riboflavin to Support a Dietary Reference Intake Review.
Show detailsLiterature searches were performed in Medline, Embase, PubMed, and Scopus in February 2021. They were not restricted to a specific time period and are presented in the following tables.
Database: Medline
Search Date: 02/25/21
| Search No. | Syntax | Results |
|---|---|---|
| 1 | Riboflavin/ or Flavin mononucleotide/ or Flavin adenine dinucleotide/ | 14,464 |
| 2 | (riboflavin or Flavin mononucleotide or Flavin adenine dinucleotide or FMN).ti,ab,kw,kf. | 14,394 |
| 3 | ("FMN" OR "FAD").mp. | 11,579 |
| 4 | 1 OR 2 OR 3 | 25,996 |
| 5 | Erythrocytes/ AND Glutathione reductase/ | 1,141 |
| 6 | Erythrocytes/ and Flavins/ | 29 |
| 7 | (erythrocyte glutathione reductase* or red blood cell glutathione reductase* or RBC glutathione reductase* or erythrocyte Flavin* or red blood cell Flavin* or RBC Flavin* or EGRAC* or E-GRAC* or E grac*).ti,ab,kw,kf. | 655 |
| 8 | 5 or 6 or 7 | 1,645 |
| 9 | 4 or 8 | 27,231 |
| 10 | Anemia/ or anemia, hemolytic/ or blood pressure/ or cardiovascular diseases/ or dermatitis, seborrheic/ or flavins/ or glossitis/ or glutathione reductase/ or growth disorders/ or hemoglobins/ or hypertension/ or Leukemia/ or Lymphoma/ or Melanoma/ or mononeuropathies/ or neoplasms/ or Nervous system diseases/ or nervous system diseases/ or nervous system malformations/ or No-Observed-Adverse-Effect Level/ or peripheral nervous system diseases/ or Pheochromocytoma/ or polyneuropathies/ or Pre-eclampsia/ or Retinoblastoma/ or Sarcoma/ or skin diseases/ or stomatitis/ or vascular stiffness/ or vitamin b 6/ | 1,527,203 |
| 11 | (Anemia or blood pressure or cancer* or cardio vascular or cardiovascular or cardio-vascular or Cheilosis or Dermatitis or E GRAC or EGRAC or EGRAC or Glossitis or growth disorder* or growth retardation or Haemoglobin* or Hemoglobin* or hyper tens* or hypertens* or hyper-tens* or leukemia* or lymphoma* or melanoma* or microcytic anemia* or neoplas* or nervous system or neurologic* or neuropath* or Pheochromocytoma* or pre eclampsia or preeclampsia or pre-eclampsia or Pyridox* or retinoblastoma* or sarcoma* or Seborrheic or Stomatitis or tumor* or Vit B 6 or Vit B6 or Vit B-6 or Vitamin B 6 or Vitamin B-6).ti,ab,kw,kf. | 4,519,018 |
| 12 | Long term adverse effects/ | 638 |
| 13 | (Toxicity or high dose* or adverse event* or adverse effect* or dose-response* or LOAEL or NOAEL).ti,ab,kw,kf. | 765,237 |
| 14 | Biological availability/ | 40,807 |
| 15 | Deficiency.fs. | 167,298 |
| 16 | (Bioavailabilit* or Bio-availabilit* or Deficien*).ti,ab,kw,kf. | 531,186 |
| 17 | 10 or 11 or 12 or 13 or 14 or 15 or 16 | 5,874,324 |
| 18 | 9 and 17 | 8,024 |
| 19 | Diet/ or dietary supplements/ or food/ | 244,052 |
| 20 | (diet* or food*).ti,ab,kw,kf. | 839,505 |
| 21 | 19 or 20 | 912,505 |
| 22 | 18 and 21 | 1,641 |
| 23 | (abstracts or academic dissertation or comment or editorial or letter or meeting abstract or meta analysis or review or systematic review).pt. | 4,343,870 |
| 24 | 22 not 23 | 1,439 |
| 25 | 24 not (Animals/ not (Animals/ and Humans/)) | 1,022 |
| 26 | limit 25 to English language | 930 |
Database: Embase
Search Date: 02/25/21
| Search No. | Syntax | Results |
|---|---|---|
| 1 | Riboflavin/ or Flavin mononucleotide/ or Flavin adenine dinucleotide/ | 21,543 |
| 2 | (riboflavin or Flavin mononucleotide or Flavin adenine dinucleotide or FMN).ti,ab,kw. | 15,583 |
| 3 | ("FMN" OR "FAD").mp. | 13,294 |
| 4 | 1 OR 2 OR 3 | 32,384 |
| 5 | Erythrocytes/ AND Glutathione reductase/ | 906 |
| 6 | Erythrocytes/ and Flavins/ | 7 |
| 7 | (erythrocyte glutathione reductase* or red blood cell glutathione reductase* or RBC glutathione reductase* or erythrocyte Flavin* or red blood cell Flavin* or RBC Flavin* or EGRAC* or E-GRAC* or E grac*).ti,ab,kw. | 680 |
| 8 | 5 or 6 or 7 | 1,461 |
| 9 | 4 or 8 | 33,533 |
| 10 | Anemia/ or anemia, hemolytic/ or blood pressure/ or cardiovascular diseases/ or dermatitis, seborrheic/ or flavins/ or glossitis/ or glutathione reductase/ or growth disorders/ or hemoglobins/ or hypertension/ or Leukemia/ or Lymphoma/ or Melanoma/ or mononeuropathies/ or neoplasms/ or Nervous system diseases/ or nervous system diseases/ or nervous system malformations/ or No-Observed-Adverse-Effect Level/ or peripheral nervous system diseases/ or Pheochromocytoma/ or polyneuropathies/ or Pre-eclampsia/ or Retinoblastoma/ or Sarcoma/ or skin diseases/ or stomatitis/ or vascular stiffness/ or vitamin b 6/ | 1,574,674 |
| 11 | (Anemia or blood pressure or cancer* or cardio vascular or cardiovascular or cardio-vascular or Cheilosis or Dermatitis or E GRAC or EGRAC or EGRAC or Glossitis or growth disorder* or growth retardation or Haemoglobin* or Hemoglobin* or hyper tens* or hypertens* or hyper-tens* or leukemia* or lymphoma* or melanoma* or microcytic anemia* or neoplas* or nervous system or neurologic* or neuropath* or Pheochromocytoma* or pre eclampsia or preeclampsia or pre-eclampsia or Pyridox* or retinoblastoma* or sarcoma* or Seborrheic or Stomatitis or tumor* or Vit B 6 or Vit B6 or Vit B-6 or Vitamin B 6 or Vitamin B-6).ti,ab,kw. | 6,699,607 |
| 12 | Long term adverse effects/ | 156,208 |
| 13 | (Toxicity or high dose* or adverse event* or adverse effect* or dose-response* or LOAEL or NOAEL).ti,ab,kw. | 1,254,488 |
| 14 | Biological availability/ | 46,687 |
| 15 | (Bioavailabilit* or Bio-availabilit* or Deficien*).ti,ab,kw. | 748,108 |
| 16 | 10 or 11 or 12 or 13 or 14 or 15 | 8,444,217 |
| 17 | 9 and 16 | 11,888 |
| 18 | Diet/ or dietary supplements/ or food/ | 281,070 |
| 19 | (diet* or food*).ti,ab,kw. | 1,172,330 |
| 20 | 18 or 19 | 1,216,750 |
| 21 | 17 and 20 | 3,508 |
| 22 | (abstracts or academic dissertation or comment or editorial or letter or meeting abstract or meta analysis or review or systematic review).pt. | 4,503,857 |
| 23 | 21 not 22 | 2,955 |
| 24 | 23 not ((exp animal/ or nonhuman/) not exp human/) | 2,375 |
| 25 | limit 24 to English language | 2,231 |
| 26 | limit 25 to (pubmed-not-medline or pubmed/medline) | 182 |
| 27 | 25 not 26 | 2,049 |
Database: PubMed
Search Date: 02/25/21
| Search No. | Syntax | Results |
|---|---|---|
| 1 | riboflavin[MeSH Terms] OR flavin mononucleotide[MeSH Terms] OR Flavin adenine dinucleotide[MeSH Terms] | 14,478 |
| 2 | riboflavin[Title/Abstract] OR "Flavin mononucleotide"[Title/Abstract] OR "Flavin adenine dinucleotide"[Title/Abstract] OR "FMN"[Title/Abstract] OR "FAD"[Title/Abstract] | 23,150 |
| 3 | #1 or #2 | 27,742 |
| 4 | Erythrocytes[MeSH Terms] AND Glutathione reductase[MeSH Terms] | 1,194 |
| 5 | Erythrocytes[MeSH Terms] AND flavins[MeSH Terms] | 433 |
| 6 | "erythrocyte glutathione reductase*"[Title/Abstract] or "red blood cell glutathione reductase*"[Title/Abstract] or "RBC glutathione reductase*"[Title/Abstract] or "erythrocyte Flavin*"[Title/Abstract] or "red blood cell Flavin*"[Title/Abstract] or "RBC Flavin*"[Title/Abstract] or "EGRAC*"[Title/Abstract] or "E-GRAC*"[Title/Abstract] or "E grac*"[Title/Abstract] | 713 |
| 7 | #4 or #5 or #6 | 1,925 |
| 8 | #3 or #7 | 29,076 |
| 9 | Anemia[MeSH Terms] or anemia, hemolytic[MeSH Terms] or blood pressure[MeSH Terms] or cardiovascular diseases[MeSH Terms] or dermatitis, seborrheic[MeSH Terms] or flavins[MeSH Terms] or glossitis[MeSH Terms] or glutathione reductase[MeSH Terms] or growth disorders[MeSH Terms] or hemoglobins[MeSH Terms] or hypertension[MeSH Terms] or Leukemia[MeSH Terms] or Lymphoma[MeSH Terms] or Melanoma[MeSH Terms] or mononeuropathies[MeSH Terms] or neoplasms[MeSH Terms] or Nervous system diseases[MeSH Terms] or nervous system diseases[MeSH Terms] or nervous system malformations[MeSH Terms] or No-Observed-Adverse-Effect Level[MeSH Terms] or peripheral nervous system diseases[MeSH Terms] or Pheochromocytoma[MeSH Terms] or polyneuropathies[MeSH Terms] or Pre-eclampsia[MeSH Terms] or Retinoblastoma[MeSH Terms] or Sarcoma[MeSH Terms] or skin diseases[MeSH Terms] or stomatitis[MeSH Terms] or vascular stiffness[MeSH Terms] or vitamin b 6[MeSH Terms] | 8,352,121 |
| 10 | Anemia[Title/Abstract] or "blood pressure"[Title/Abstract] or cancer*[Title/Abstract] or "cardio vascular"[Title/Abstract] or cardiovascular[Title/Abstract] or "cardio-vascular"[Title/Abstract] or Cheilosis[Title/Abstract] or Dermatitis[Title/Abstract] or "E GRAC"[Title/Abstract] or "EGRAC"[Title/Abstract] or "EGRAC"[Title/Abstract] or Glossitis[Title/Abstract] or "growth disorder*"[Title/Abstract] or "growth retardation"[Title/Abstract] or Haemoglobin*[Title/Abstract] or Hemoglobin*[Title/Abstract] or "hyper tens*"[Title/Abstract] or hypertens*[Title/Abstract] or "hypertens*"[Title/Abstract] or leukemia*[Title/Abstract] or lymphoma*[Title/Abstract] or melanoma*[Title/Abstract] or "microcytic anemia*"[Title/Abstract] or neoplas*[Title/Abstract] or "nervous system"[Title/Abstract] or neurologic*[Title/Abstract] or neuropath*[Title/Abstract] or Pheochromocytoma*[Title/Abstract] or "pre eclampsia"[Title/Abstract] or preeclampsia[Title/Abstract] or "preeclampsia"[Title/Abstract] or Pyridox*[Title/Abstract] or retinoblastoma*[Title/Abstract] or sarcoma*[Title/Abstract] or Seborrheic[Title/Abstract] or Stomatitis[Title/Abstract] or tumor*[Title/Abstract] or "Vit B 6"[Title/Abstract] or "Vit B6"[Title/Abstract] or "Vit B-6"[Title/Abstract] or "Vitamin B 6"[Title/Abstract] or "Vitamin B-6"[Title/Abstract] | 5,171,542 |
| 11 | Long term adverse effects[MeSH terms] | 638 |
| 12 | Toxicity[Title/Abstract] or "high dose*"[Title/Abstract] or "adverse event*"[Title/Abstract] or "adverse effect*"[Title/Abstract] or "dose-response*" [Title/Abstract] or "LOAEL"[Title/Abstract] or "NOAEL"[Title/Abstract] | 882,680 |
| 13 | Biological availability[MeSH Terms] | 40,843 |
| 14 | Bioavailabilit*[Title/Abstract] or "Bio-availabilit*"[Title/Abstract] or Deficien*[Title/Abstract] | 5,96,012 |
| 15 | #9 or #10 or #11 or #12 or #13 or #14 | 10,739,352 |
| 16 | #8 and #15 | 20,260 |
| 17 | Diet[MeSH Terms] or dietary supplements[MeSH Terms] or food[MeSH Terms] | 827,411 |
| 18 | diet*[Title/Abstract] or food*[Title/Abstract] | 984,410 |
| 19 | #17 or #18 | 1,440,705 |
| 20 | #16 and #19 | 3,713 |
| 21 | comment [Publication Type] or editorial [Publication Type] or letter [Publication Type] or meta analysis [Publication Type] or review [Publication Type] or systematic review [Publication Type] | 4,761,910 |
| 22 | #20 not #21 | 3,356 |
| 23 | #22 NOT ("Animals"[Mesh] NOT ("Animals"[Mesh] AND "Humans"[Mesh])) | 2,048 |
| 24 | #24 and (pubmednotmedline[sb]) | 86 |
| Filter: English[Language] |
Database: Scopus
Search Date: 02/26/21
( ( ( TITLE-ABS-KEY ( ( RIBOFLAVIN OR "FLAVIN MONONUCLEOTIDE" OR "FLAVIN ADENINE DINUCLEOTIDE" OR "FMN" OR "FAD" OR "ERYTHROCYTE GLUTATHIONE REDUCTASE*" OR "RED BLOOD CELL GLUTATHIONE REDUCTASE*" OR "RBC GLUTATHIONE REDUCTASE*" OR "ERYTHROCYTE FLAVIN*" OR "RED BLOOD CELL FLAVIN*" OR "RBC FLAVIN*" OR "EGRAC*" OR "E-GRAC*" OR "E GRAC*" ) AND ( ANEMIA OR "BLOOD PRESSURE" OR CANCER* OR "CARDIO VASCULAR" OR CARDIOVASCULAR OR "CARDIO-VASCULAR" OR CHEILOSIS OR DERMATITIS OR "E GRAC" OR "EGRAC" OR "E-GRAC" OR GLOSSITIS OR "GROWTH DISORDER*" OR "GROWTH RETARDATION" OR HAEMOGLOBIN* OR HEMOGLOBIN* OR "HYPER TENS*" OR HYPERTENS* OR "HYPER-TENS*" OR LEUKEMIA* OR LYMPHOMA* OR MELANOMA* OR "MICROCYTIC ANEMIA*" OR NEOPLAS* OR "NERVOUS SYSTEM" OR NEUROLOGIC* OR NEUROPATH* OR PHEOCHROMOCYTOMA* OR "PRE ECLAMPSIA" OR PREECLAMPSIA OR "PREECLAMPSIA" OR PYRIDOX* OR RETINOBLASTOMA* OR SARCOMA* OR SEBORRHEIC OR STOMATITIS OR TUMOR* OR "VIT B 6" OR "VIT B6" OR "VIT B-6" OR "VITAMIN B 6" OR "VITAMIN B-6" OR TOXICITY OR "HIGH DOSE*" OR "ADVERSE EVENT*" OR "ADVERSE EFFECT*" OR "DOSE-RESPONSE*" OR "LOAEL" OR "NOAEL" OR BIOAVAILABILIT* OR "BIO-AVAILABILIT*" OR DEFICIEN* ) ) ) AND ( TITLE-ABS-KEY ( DIET* OR FOOD* ) ) ) AND ( INDEXTERMS ( HUMAN* ) OR TITLE-ABS-KEY ( HUMAN* ) ) ) AND NOT ( INDEX ( MEDLINE ) ) AND ( EXCLUDE ( DOCTYPE , "RE" ) OR EXCLUDE ( DOCTYPE , "LE" ) OR EXCLUDE ( DOCTYPE , "ED" ) OR EXCLUDE ( DOCTYPE , "CH" ) ) AND ( LIMIT-TO ( LANGUAGE , "ENGLISH" ) )
- Literature Searches - Scanning for New Evidence on Riboflavin to Support a Dieta...Literature Searches - Scanning for New Evidence on Riboflavin to Support a Dietary Reference Intake Review
- ankyrin repeat-containing protein ITN1-like [Benincasa hispida]ankyrin repeat-containing protein ITN1-like [Benincasa hispida]gi|1955841592|ref|XP_038878763.1|Protein
- dab24d08.y1 NICHD_XGC_Sp1 Xenopus laevis cDNA clone IMAGE:4175294 5' similar to ...dab24d08.y1 NICHD_XGC_Sp1 Xenopus laevis cDNA clone IMAGE:4175294 5' similar to TR:O60927 O60927 HCG V, mRNA sequencegi|13314302|gnl|dbEST|8129537|gb|BG 3.1|Nucleotide
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