Further time points: results from the intervention-level network meta-analysis

Deborah M Caldwell; Sarah R Davies; Joanna C Thorn; Jennifer C Palmer; Paola Caro; Sarah E Hetrick; David Gunnell; Sumayya Anwer; José A López-López; Clare French; Judi Kidger; Sarah Dawson; Rachel Churchill; James Thomas; Rona Campbell; Nicky J Welton

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Caldwell DM, Davies SR, Thorn JC, et al. School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis. Southampton (UK): NIHR Journals Library; 2021 Jul. (Public Health Research, No. 9.8.)

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School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis.

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Appendix 5Further time points: results from the intervention-level network meta-analysis

TABLE 55

Results from the intervention-level network meta-analysis: further time points for anxiety outcome

Population and setting	Intervention	Reference	Follow-up (months)
			6–12		13–24		≥ 25
			SMD	95% CrI	SMD	95% CrI	SMD	95% CrI
Universal, secondary	CBT	Usual curriculum	–0.11	–0.34 to 0.11	–0.01	–2.84 to 2.81	–0.23	–0.55 to 0.08
	Third wave	Usual curriculum	–0.05	–0.32 to 0.22	–	–	–	–
	CBT + IPT	Usual curriculum	–0.02	–0.42 to 0.36	–	–	–	–
Universal, primary	CBT	Usual curriculum	–0.11	–0.35 to 0.11	0.00	–0.68 to 0.71	–0.12	–0.26 to 0.02
Targeted, secondary	CBT	No intervention	0.05	–0.12 to 0.20	–0.26	–0.52 to –0.01^a	–0.39	–0.65 to –0.14^a
Targeted, secondary	CBM	No intervention	–0.14	–0.53 to 0.24	–	–	–	–
Targeted, primary	CBT	Waiting list	–0.17	–1.37 to 1.06	–	–	–	–
Targeted, primary	Biofeedback	Waiting list	–0.28	–2.49 to 1.93	–	–	–	–

a: Single study.

TABLE 56

Results from the intervention-level network meta-analysis: further time points for depression outcome

Population and setting	Intervention	Reference	Follow-up (months)
			6–12		13–24		≥ 25
			SMD	95% CrI	SMD	95% CrI	SMD	95% CrI
Universal, secondary	CBT	Usual curriculum	–0.02	–0.10 to 0.06	–0.04	–0.20 to 0.14	–0.14	–2.89 to 2.63
	Third wave	Usual curriculum	–0.13	–0.27 to 0.01	–	–	–	–
	CBT + IPT	Usual curriculum	–0.10	–0.26 to 0.05	–0.10	–0.57 to 0.39	–	–
	IPT	Usual curriculum	0.11	–0.13 to 0.35	–	–	–	–
Universal, primary	CBT	Usual curriculum	–0.15	–0.43 to 0.09	–0.03	–0.62 to 0.55	–0.27	–0.42 to –0.13^a
Targeted, secondary	CBT	No intervention	–0.04	–0.51 to 0.41	–0.18	–2.56 to 2.16	–0.27	–1.05 to 0.50^a
Targeted, secondary	IPT	No intervention	–0.49	–1.49 to 0.48	0.09	–3.81 to 3.93	–	–
Targeted, primary	CBT	Waiting list	–0.34	–0.72 to 0.05^b	–0.50	–0.96 to 0.05^a	–	–

a: Single study.
b: Fixed effect.

Copyright © Queen’s Printer and Controller of HMSO 2021. This work was produced by Caldwell et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

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Caldwell DM, Davies SR, Thorn JC, et al. School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis. Southampton (UK): NIHR Journals Library; 2021 Jul. (Public Health Research, No. 9.8.) Appendix 5, Further time points: results from the intervention-level network meta-analysis.
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