Figure 1. Histology of hepatoblastoma.

Figure 1

Histology of hepatoblastoma. A. Slice following partial resection of the liver showing a hepatoblastoma with grey cut surface and small areas of hemorrhages. B. Microphotograph showing hepatoblastoma with pure fetal histology and minimal mitotic activity (hematoxylin and eosin staining, x200 original magnification). C. Microphotograph showing hepatoblastoma of embryonal type (hematoxylin and eosin staining, x200 original magnification). D. Microphotograph showing a teratoid hepatoblastoma with ribbons and nephroblastoma-like tubules and acini (hematoxylin and eosin staining, x50 original magnification, scale bar: 100 micrometers). E. Microphotograph showing lung metastasis of a hepatoblastoma with two nodules depicting hemosiderin accumulation (blue) both inside and at the edges of the tumor clusters. The lung tissue in the middle of the microphotograph shows the characteristic alveolar pattern. Perls’ Prussian Blue (PPB) has its name from the 19th century German pathologist Max Perls, who introduced this technique in histopathology to stain iron in the ferric state (e.g., ferritin and hemosiderin (Perls’ Prussian Blue, x50 original magnification, scale bar: 100 micrometers). F. Microphotograph showing a hepatoblastoma post chemotherapy exhibiting some cell maturation (right) and some hemorrhage (center). Some fibrosis is encountered on the left side of the microphotograph (hematoxylin and eosin staining, x200 original magnification).

From: Chapter 8, Hepatoblastoma

Cover of Liver Cancer
Liver Cancer [Internet].
Sergi CM, editor.
Brisbane (AU): Exon Publications; 2021 Apr 6.
Copyright: The Authors.

Licence: This open access article is licensed under Creative Commons Attribution 4.0 International (CC BY 4.0). https://creativecommons.org/licenses/by-nc/4.0/

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