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Smith GCS, Moraitis AA, Wastlund D, et al. Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis. Southampton (UK): NIHR Journals Library; 2021 Feb. (Health Technology Assessment, No. 25.15.)

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Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis.

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Appendix 1Supporting data for the systematic review of the diagnostic effectiveness of universal ultrasonic screening using late pregnancy umbilical artery Doppler flow velocimetry in the prediction of adverse perinatal outcome

MEDLINE and EMBASE

Date range searched: inception to 19 March 2019.

Search strategy

  1. exp pregnant woman/
  2. exp pregnancy/
  3. pregnan*.mp.
  4. exp prenatal diagnosis/
  5. exp fetus echography/
  6. exp Doppler ultrasonography/
  7. arterial doppler.mp.
  8. doppler velocimetry.mp.
  9. doppler ultraso*.mp.
  10. umbilical arter*.mp.
  11. 1 or 2 or 3
  12. 4 or 5 or 6
  13. 7 or 8 or 9 or 10
  14. 11 and 12
  15. 13 and 14.
FIGURE 25. The POP study inclusion flow chart.

FIGURE 25

The POP study inclusion flow chart. USS, ultrasound scan.

TABLE 18

TABLE 18

Maternal characteristics and birth outcomes of POP study

FIGURE 26. Literature search PRISMA flow diagram for the systematic review on umbilical artery Doppler.

FIGURE 26

Literature search PRISMA flow diagram for the systematic review on umbilical artery Doppler.

FIGURE 27. Risk of bias and applicability concerns using the QUADAS-2 tool for the studies included in the meta-analysis of umbilical artery Doppler.

FIGURE 27

Risk of bias and applicability concerns using the QUADAS-2 tool for the studies included in the meta-analysis of umbilical artery Doppler.

TABLE 19

TABLE 19

Characteristics of studies included in the meta-analysis

FIGURE 28. Deeks’ funnel plot for publication bias for umbilical artery Doppler for the prediction of neonatal unit admission.

FIGURE 28

Deeks’ funnel plot for publication bias for umbilical artery Doppler for the prediction of neonatal unit admission. Deeks’ funnel plot asymmetry test, p = 0.52. ESS, effective sample size.

Copyright © 2021 Smith et al. This work was produced by Smith et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaption in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.
Bookshelf ID: NBK568302
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