Copyright Notice
Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Bookshelf ID: NBK567877PMID: 33630479
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 135729-61-2
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of palonosetron during breastfeeding. Until more data become available, palonosetron should be used with caution during breastfeeding. An alternate drug may be preferred.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Substance Identification
Substance Name
Palonosetron
CAS Registry Number
135729-61-2
Drug Class
Breast Feeding
Antiemetics
Gastrointestinal Agents
Serotonin Antagonists
Serotonin 5-HT3 Receptor Antagonists
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubChem SubstanceRelated PubChem Substances
- Review Treprostinil.[Drugs and Lactation Database (...]Review Treprostinil.. Drugs and Lactation Database (LactMed®). 2006
- Review Granisetron.[Drugs and Lactation Database (...]Review Granisetron.. Drugs and Lactation Database (LactMed®). 2006
- The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro.[Br J Pharmacol. 1995]The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro.Wong EH, Clark R, Leung E, Loury D, Bonhaus DW, Jakeman L, Parnes H, Whiting RL, Eglen RM. Br J Pharmacol. 1995 Feb; 114(4):851-9.
- 2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists.[J Med Chem. 1993]2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists.Clark RD, Miller AB, Berger J, Repke DB, Weinhardt KK, Kowalczyk BA, Eglen RM, Bonhaus DW, Lee CH, Michel AD. J Med Chem. 1993 Sep 3; 36(18):2645-57.
- Review Tolazamide.[Drugs and Lactation Database (...]Review Tolazamide.. Drugs and Lactation Database (LactMed®). 2006
- Palonosetron - Drugs and Lactation Database (LactMed®)Palonosetron - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...