Scaffold 2.

Scaffold 2

SID-87235990

Synthesis of SID-87235990 (liquid SID-3713089)

(i) Mel, NaOH, MW, 2 min, 80°C, 56%. (ii) Hydrazine hydrate, 2-propanol, reflux, 2h, 61%. (iii) N-Acetoacetyl-p-toluidine, Lawesson’s reagent, 55°C, 12h, 95%.

From: Small Molecule Inhibitors of Wee1 Degradation and Mitotic Entry

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

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