Fig. 2. Effect of craniectomy on the field and current distribution in a human head model.

Fig. 2

Effect of craniectomy on the field and current distribution in a human head model. (Reproduced from Korshoej et al. [17]). (a) Surface representations of a patient’s head with the left/right (L/R) and anterior/posterior (A/P) array pairs positioned on the scalp. The middle panel shows the current density distribution on the brain surface induced by the corresponding array configurations in the presence of a craniectomy (encircled) above the tumor region. Compared to a situation with no craniectomy (right-most panels), it is clear that craniectomy causes a significant amount of current to flow through the craniectomy and toward the underlying brain region. (b) This panel shows results similar to (a), but with the current distributions shown for the skin and electrode surfaces, respectively. The craniectomy redistributes how the impressed currents flow through the electrodes, and more importantly it causes a lower amount of current to flow through the skin between the electrodes and rather redirects the current toward the brain region underneath the hole in the skull

From: Improving Tumor-Treating Fields with Skull Remodeling Surgery, Surgery Planning, and Treatment Evaluation with Finite Element Methods

Cover of Brain and Human Body Modeling 2020
Brain and Human Body Modeling 2020: Computational Human Models Presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting [Internet].
Makarov SN, Noetscher GM, Nummenmaa A, editors.
Cham (CH): Springer; 2021.
Copyright 2021, The Author(s)

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