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Drug Class	Drug	Dose Range	Adverse Effects/Contraindications
Beta-adrenoceptor blockers[78]	Propranolol Metoprolol Timolol	80-240 mg 50-150 mg 10-20 mg	Contraindicated in asthma, syncope, heart block
Antidepressants	Amitriptyline Nortriptyline Venlafaxine	10-150 mg 25-100 mg 37.5-150 mg	Somnolence Insomnia, hypertension
Calcium-channel blockers	Verapamil[79]	180-480 mg	Constipation, hypotension, edema
Antiepileptic drugs[78]	Divalproex sodium Topiramate Gabapentin	200-1500 mg 25-150 mg 300-1800 mg	Weight gain, thrombocytopenia, tremor Renal calculi, amnesia, glaucoma, dysequilibrium, weight loss
CGRP monoclonal antibodies	Erenumab Galcanezumab	70 to 140 mg every four weeks, subcutaneously 120 mg monthly subcut	Injection site reactions, muscle spasms, hypersensitivity reaction Injection site reactions, vertigo, pruritus, constipation