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Chou R, Hartung D, Turner J, et al. Opioid Treatments for Chronic Pain [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2020 Apr. (Comparative Effectiveness Review, No. 229.)

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Opioid Treatments for Chronic Pain [Internet].

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Figure 21 is a forest plot reporting mean difference of improvement in mean SF-36 mental health measures for opioids plus nonopioids versus nonopioids. Data for figure 21 is presented in Table 17. The overall mean difference for all studies is −2.92 (95% CI −6.30 to 0.46). This figure is described further in the Results section under Key Question 1d under opioids plus nonopioids versus nonopioids detailed synthesis.

Figure 21Meta-analysis of improvement in mean SF-36 mental health measures for opioids plus nonopioids versus nonopioids

Abbreviations: CI=confidence interval; EERWD=enriched enrollment randomized withdrawal design; GBP=gabapentin; N=sample size; NR=not reported; NTTL=nortryptiline; PGB=pregabalin; SD=standard deviation; SF-36 MCS= Short Form-36 Meantal Component Scale; SF-36 MH=Short Form-36 Mental Health.

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