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Skelly AC, Chou R, Dettori JR, et al. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2020 Apr. (Comparative Effectiveness Review, No. 227.)

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Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update [Internet].

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Table 33Osteoarthritis hand pain: exercise

Author, Year, Followup,a Pain Duration, Study QualityInterventionPopulationFunction and Pain OutcomesOther Outcomes

Osteras, 201475

3 months

Duration of pain: NR

Poor

A. Exercise (n=46): ROM/strength exercises, 4 group sessions supplemented by instructions for home exercise 3 times per week for 12 weeks

B. Usual care (n=64): Subjects received no particular attention, referral, or treatment from the study.

A vs. B

Age: 67 vs. 65 years

Females: 89% vs. 91%

Fulfillment of ACR criteria for hand OA 91% vs. 91%

Self-reported hip OA: 39% vs. 46%

Self-reported knee OA: 40% vs. 51%

Other rheumatic disease: 13% vs. 15%

Severe mental distress: 17% vs. 39%

Baseline FIHOA (0-30): 10.8 vs. 9.8

PSFS (0-10): 3.5 vs. 3.9

Baseline hand pain NRS (0-10): 4.2 vs. 3.9

A vs. B

3 months

FIHOA: 10.9 vs. 10.5; adjusted difference −0.5 (95% CI −1.9 to 0.8)

Hand pain NRS: 4.3 vs. 4.3; adjusted difference −0.2 (95% CI −0.8 to 0.3)

OARSI OMERACT no. of responders: 30% vs. 28% (NS)

A vs. B

3 months

PSFS (0-10): 4.3 vs. 4.4; adjusted difference 0.1 (95% CI −0.7 to 1.0)

Patient global assessment of disease activity (0-10): 4.2 vs. 4.1; adjusted difference 0.1 (95% CI −0.5 to 0.7)

Patient global assessment of disease activity affecting ADL: 3.8 vs. 3.8; adjusted difference −0.2 (95% CI −0.8 to 0.4)

ACR = American College of Radiology; ADL = activity of daily living; CI = confidence interval; FIHOA = Functional Index for Hand OsteoArthritis; NR = not reported; NRS = numeric rating scale; NS = not statistically significant; OA = osteoarthritis; OARSI OMERACT = Osteoarthritis Research Society International Outcome Measures in Rheumatology; PSFS = patient-specific function scale; ROM = range of motion

a

Unless otherwise noted, followup time is calculated from the end of the treatment period

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