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Skelly AC, Chou R, Dettori JR, et al. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2020 Apr. (Comparative Effectiveness Review, No. 227.)

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Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update [Internet].

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Table 50Chronic neck pain: effects of nonpharmacological interventions compared with usual care, placebo, sham, attention control, or waitlista

Intervention

Function

Short-Term

Effect Size SOE

Function

Intermediate-Term

Effect Size SOE

Function

Long-Term

Effect Size SOE

Pain

Short-Term

Effect Size SOE

Pain

Intermediate-Term

Effect Size SOE

Pain

Long-Term

Effect Size SOE

Exercise

none

+

none

+

small

+

none

+

none

+

none

+

Psychological Therapies: PT-Led Relaxation Training

none

+

none

+

no evidence

none

+

none

+

no evidence
Physical Modalities: Low-Level Laser Therapy

moderate

++

no evidenceno evidence

moderate

++

no evidenceno evidence
Physical Modalities: Traction, Electromagnetic fieldinsufficient evidenceno evidenceno evidenceinsufficient evidenceno evidenceno evidence
Manual Therapies: Massage

smallb

+

none

+

no evidence

moderatec

+

no evidenceno evidence
Mind-Body Practices: Alexander Technique

small

+

small

+

no evidenceno evidenceno evidenceno evidence
Acupuncture

small

+

small

+

none

+

none

+

none

+

none

+

Short-Term: 1 to <6 months; Intermediate-Term: ≥6 to <12 months; Long-Term: ≥12 months

Effect Size: none, small, moderate, or large improvement

Strength of Evidence: + = low, ++ = moderate, +++ = high

none = no effect/no statistically significant effect; PT = physical therapist; SOE = strength of evidence.

a

SOE and effect size based on totality of evidence from prior report and new trials.

b

Effect size upgraded one level from prior report.

c

There was no evidence for short-term pain in the prior report.

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