Table 5.4, [The modified Boston criteria for cerebral amyloid angiopathy (CAA)]. - Diseases of the Brain, Head and Neck, Spine 2020–2023

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Hodler J, Kubik-Huch RA, von Schulthess GK, editors. Diseases of the Brain, Head and Neck, Spine 2020–2023: Diagnostic Imaging [Internet]. Cham (CH): Springer; 2020. doi: 10.1007/978-3-030-38490-6_5

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Table 5.4

The modified Boston criteria for cerebral amyloid angiopathy (CAA)

Definite CAA	Full post-mortem examination	• Lobar, cortical, or cortical/subcortical hemorrhage • Pathological evidence of severe cerebral amyloid angiopathy • Absence of other diagnostic lesion
Probable CAA with supporting pathology	Clinical data and pathological tissue (evacuated hematoma or cortical biopsy specimen)	• Lobar, cortical, or corticosubcortical hemorrhage • Some degree of CAA in specimen • Absence of other diagnostic lesion
Probable CAA	Clinical data	• Patient 55 years or older • Absence of other diagnostic lesion • Absence of other cause of hemorrhage or superficial siderosis
Probable CAA	MRI or CT demonstrating	• Multiple hemorrhages restricted to lobar, cortical, or corticosubcortical regions (cerebellar hemorrhages allowed) of varying sizes/agesOr • Single lobar, cortical, or corticosubcortical hemorrhage and focal (three or less sulci) or disseminated (more than three sulci) cortical superficial siderosis
Possible CAA	Clinical data	• Patient 55 years or older • Absence of other cause of hemorrhage or superficial siderosis
Possible CAA	MRI or CT demonstrating	• Single lobar, cortical, or corticosubcortical hemorrhageOr • Focal or disseminated superficial siderosis

From: Chapter 5, Nontraumatic Intracranial Hemorrhage

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Vilela P, Wiesmann M. Nontraumatic Intracranial Hemorrhage. 2020 Feb 15. In: Hodler J, Kubik-Huch RA, von Schulthess GK, editors. Diseases of the Brain, Head and Neck, Spine 2020–2023: Diagnostic Imaging [Internet]. Cham (CH): Springer; 2020. Table 5.4, [The modified Boston criteria for cerebral amyloid angiopathy (CAA)]. doi: 10.1007/978-3-030-38490-6_5
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