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Bille JF, editor. High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics [Internet]. Cham (CH): Springer; 2019. doi: 10.1007/978-3-030-16638-0_17

Cover of High Resolution Imaging in Microscopy and Ophthalmology

High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics [Internet].

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Fig. 17.1. The retina and photoreceptor mosaic.

Fig. 17.1

The retina and photoreceptor mosaic. (a) Hematoxylin and eosin stain of a human retina in cross section. Light entering the eye (arrows) passes through dense layers of neuronal cells and blood vessels (asterisks) before it is absorbed in the outer segments of the photoreceptors. ILM inner limiting membrane, NFL nerve fiber layer, GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer, ONL outer nuclear layer, OLM outer limiting membrane, IS photoreceptor inner segments, OS photoreceptor outer segments, RPE retinal pigment epithelium, BM Bruch’s membrane, CHO anterior part of the choroid. (b) In a macaque retinal flat mount at ~3° eccentricity (~0.6 mm away from the foveal center) photographed with differential interference contrast microscopy, cone inner segments are visible as closely packed circular structures, interspersed with a few smaller rod inner segments.(c) In vivo AOSLO imaging of cones from another macaque, also at 3° eccentricity. Rods are unresolved in this image, but are likely to be nestled in the dark gaps between cones

From: Chapter 17, Adaptive Optics for Photoreceptor-Targeted Psychophysics

Copyright 2019, The Author(s)

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