Days After
Starting
Days After
Stopping
ALT
(U/L)
Alk P
(U/L)
Bilirubin
(mg/dL)
Comment

-21

32

129

0.2

0 (1st dose)

30

125

0.3

Durvalumab started

7

190

107

0.4

21 (2nd dose)

38

120

0.4

28

112

114

0.3

42 (3rd dose)

25

99

0.4

49

43

86

0.3

63 (4th dose)

17

98

0.3

70

41

109

0.4

84 (5th dose)

26

105

0.4

91

33

89

0.4

105 (dose held)

0

417

511

0.6

Prednisone (1 mg/kg)

114

9

86

293

0.4

Prednisone taper

119

14

54

245

0.4

126

21

70

244

0.4

133

28

165

312

0.4

140

35

267

713

0.3

Prednisone dose increase

162

57

67

499

0.6

176

71

34

109

1.2

Azathioprine added

232

127

51

61

1.4

Prednisone stopped

301

196

39

72

0.7

Normal Values

<45

<130

<1.2

From: Durvalumab

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