Table 3, Characteristics of Included Primary Clinical Study - One Dose of Doxycycline for the Prevention of Lyme Disease: A Review of Clinical Effectiveness and Guidelines

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Sutton D, Spry C. One Dose of Doxycycline for the Prevention of Lyme Disease: A Review of Clinical Effectiveness and Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 May 21.

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One Dose of Doxycycline for the Prevention of Lyme Disease: A Review of Clinical Effectiveness and Guidelines [Internet].

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Table 3Characteristics of Included Primary Clinical Study

First Author, Publication Year, Country	Study Design	Population Characteristics	Intervention and Comparator(s)	Clinical Outcomes, Length of Follow-Up
Non-Randomized Study
Jackson et al, 2014, United States of America²⁰	Prospective Cohort Study	Patients presenting to a pharmacy in Rhode Island aged 18 years or older with an Ixodes scapularis tick attached for 36 hours or more and intervention was administered within 72 hours of tick removal.	Intervention: - Doxycycline (two 100 mg tablets taken as a single dose with food)	- Any signs or symptoms of Lyme disease at any time within 30 days after intervention. - Adverse effects within 30 days after intervention.

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Sutton D, Spry C. One Dose of Doxycycline for the Prevention of Lyme Disease: A Review of Clinical Effectiveness and Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 May 21. Table 3, Characteristics of Included Primary Clinical Study.
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