Identified randomised controlled trials meeting inclusion criteria

Rod S Taylor; Sarah Walker; Oriana Ciani; Fiona Warren; Neil A Smart; Massimo Piepoli; Constantinos H Davos

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Taylor RS, Walker S, Ciani O, et al. Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis. Southampton (UK): NIHR Journals Library; 2019 May. (Health Technology Assessment, No. 23.25.)

Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis.

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Appendix 3Identified randomised controlled trials meeting inclusion criteria

First author/study (year)	Total patients (n)^a	Trial setting (single or multicentre)	NYHA class	Mean ejection fraction (%)	Mean age (years)	Male (%)	Exercise type^b	Overall exercise duration (minutes)	Exercise frequency (sessions/week)	Mean programme duration (weeks)	Exercise setting^c	Longest follow-up (months)
Cochrane 2014 review
Austin et al. (2005)⁷⁰	200	Single	II/III	NR	72	43	Mix	120	2.5	24	Both	60
Belardinelli et al. (1999)⁵⁰	99	Single	II/IV	28	55	89	Aerobic	40	2.5	56	Centre	26
Belardinelli et al. (2012)⁵⁶	123	Single	II/III	37	59	78	Aerobic	40	2.5	56	Centre	120
Davidson et al. (2010)⁶⁹	105	Single	I/II/III/IV	NR	72.3	67	Mix	40	1	12	Centre	12
Dracup et al. (2007)⁵⁸	173	Single	II/IV	26	54	72	Mix	28	4	52	Home	12
DANREHAB (2008)⁵⁷	91	Single	I/II/III	NR	66	90	Mix	90	3	12	Both	12
Gary et al. (2010)⁵⁹	65	Single	II/III	NR	65.8	42	Aerobic	37.5	3	12	Home	6
Giannuzzi et al. (2003)⁶⁰	90	Multi	II/III	25	60.5	88	Aerobic	30	4	24	Both	6
Hambrecht et al. (2000)⁵¹	73	Single	I/II/III	29	54	100	Aerobic	15	6.5	24	Both	6
HF-ACTION (2009)¹⁹	2331	Multi	II/III/IV	25	59	72	Aerobic	30	2.5	120	Both	48
Jolly et al. (2009)⁶¹	169	Multi	I/II/IV	NR	66	75	Mix	25	5	48	Home	12
Klecha et al. (2007)⁷¹	50	Single	II/III	28	61	100	Aerobic	20	3	24	Centre	6
McKelvie et al. (2002)⁵²	181	Multi	I/II/III	NR	65.5	81	Mix	30	2	36	Both	12
Mueller et al. (2007)⁶²	50	Single	NR	NR	55	100	Aerobic	120	5	4	Centre	74
Nilsson et al. (2008)⁶³	80	Single	II/III	31	70	79	Aerobic	50	2	16	Centre	12
Passino et al. (2006)⁶⁷	95	Single	I/II/III	34	60.5	87	Aerobic	30	3	36	Home	9
Willenheimer (2001)⁵⁴	54	Single	NR	36.5	64	71.5	Aerobic	30	2.5	16	Centre	10
Witham et al. (2005)⁶⁴	82	Single	II/III	NR	80.5	55	Mix	20	2.5	24	Both	6
Witham et al. (2012)⁶⁵	107	Single	II/III	NR	81	100	Mix	60	2	24	Both	6
Yeh et al. (2011)⁶⁶	100	Multi	I/II/III	29	67.5	64	Aerobic	30	2.5	12	Both	6
ExTraMATCH I (2004)
Dubach et al. (1997);⁷² Myers (2002)⁸²	51	NR	NR	NR	NR	NR	NR	NR	NR	NR	NR	8.5
Zanelli et al. (1997)⁵⁵	155	NR	NR	NR	NR	NR	NR	NR	NR	NR	NR	10
Wielenga et al. (1999)⁵³	80	NR	NR	NR	NR	NR	NR	NR	NR	NR	NR	47.3

: DANREHAB, DANish Cardiac ReHABilitation trial; NR, not reported.
a: Total number of patients randomised.
b: ‘Mix’ includes aerobic and resistance training.
c: Exercise settings comprise home, centre or both.
: Reprinted from International Journal of Cardiology, Vol. 174, Taylor et al.²⁷ Exercise training for chronic heart failure (ExTraMATCH II): protocol for an individual participant data meta-analysis., pp. 683–7, © 2014 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved., with permission from Elsevier. www.sciencedirect.com/journal/international-journal-of-cardiology.

Copyright © Queen’s Printer and Controller of HMSO 2019. This work was produced by Taylor et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

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Taylor RS, Walker S, Ciani O, et al. Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis. Southampton (UK): NIHR Journals Library; 2019 May. (Health Technology Assessment, No. 23.25.) Appendix 3, Identified randomised controlled trials meeting inclusion criteria.
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Appendix 3Identified randomised controlled trials meeting inclusion criteria

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