This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the National Research Council’s Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report:

• Margaret A. Breida, Senior Manager, Standards and Technical Groups, American Industrial Hygiene Association, Fairfax, VA
• Dennis Devlin, Director of Toxicology and Environmental Sciences, Department of Biomedical Sciences, ExxonMobil Corporation, Annandale, NJ
• Katherine Herz, International Life Sciences Institute, Washington, DC
• Leyla McCurdy, Senior Director of Health and Environment, National Environmental Education and Training Foundation, Washington, DC

Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the final draft of the report before its release. The review of this report was overseen by Melvin H. Worth, M.D., Scholar-in-Residence, Institute of Medicine, who was responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution.report rests entirely with the authoring committee and the institution.