This volume presents papers on the topics covered at the National Academy of Engineering's 2018 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2018 symposium was held September 5-7 and hosted by MIT Lincoln Laboratory in Lexington, Massachusetts. The intent of this book is to convey the excitement of this unique meeting and to highlight innovative developments in engineering research and technical work.

Contents

• The National Academies of SCIENCES • ENGINEERING • MEDICINE
• ORGANIZING COMMITTEE
• Preface
• QUANTUM COMPUTERS: ARE WE THERE YET?
  • Quantum Computers: Are We There Yet?
    GRACE METCALFE and JERRY CHOW.
  • Quantum Computing: What It Is, Why We Want It, and How We're Trying to Get It
    SARA GAMBLE.
    • WHAT IS QUANTUM COMPUTING?
    • WHY DO WE WANT IT?
    • HOW ARE WE TRYING TO GET IT?
    • CONCLUSIONS AND OUTLOOK
    • REFERENCES
  • Quantum Algorithms: Promise and Perspective
    SHELBY KIMMEL.
    • EXAMPLES OF QUANTUM ALGORITHMS
    • WHY QUANTUM COMPUTERS ARE USEFUL FOR SOME PROBLEMS AND NOT OTHERS
    • THE FUTURE OF QUANTUM ALGORITHMS
    • CONCLUSION
    • REFERENCES
  • Quantum Computing with Noisy Qubits
    SARAH SHELDON.
    • INTRODUCTION
    • SURFACE CODE
    • HYBRID QUANTUM COMPUTING
    • LOOKING FORWARD
    • REFERENCES
  • Quantum Simulation: Advances, Platforms, and Applications
    NORMAN YAO.
    • MANY-BODY PHASES IN ULTRACOLD ATOMIC SYSTEMS
    • SPIN LIQUIDS IN POLAR MOLECULES
    • QUANTUM WALKS IN SUPERCONDUCTING QUBITS
    • CONCLUSION
    • REFERENCES
• THE ROLE OF ENGINEERING IN THE FACE OF CONFLICT AND DISASTER
  • The Role of Engineering in the Face of Conflict and Disaster
    FRANCESCA D'ARCANGELO and MIRA OLSON.
  • Engineering for the People: Putting Peace, Social Justice, and Environmental Protection at the Heart of All Engineering
    DARSHAN MUKESH ARVINDA KARWAT.
    • BACKGROUND: THE HISTORY AND PRESENT OF ENGINEERING ARE COMPLICATED
    • CURRENT EXAMPLES OF CONCERN
    • LET'S GRAPPLE WITH VALUES
    • CONCLUDING THOUGHTS
    • REFERENCES
  • Combining Formal and Informal Structures in Crisis Response
    WILLOW BRUGH, GALIT SOROKIN, and GERALD R. SCOTT.
    • INTRODUCTION
    • BACKGROUND: FORMAL AND INFORMAL RESPONSE GROUPS
    • THE NEED FOR COORDINATION
    • ORGANIZATIONAL THEORY, COLLABORATION, AND COOPERATION
    • THE PROJECT
    • IMPLICATIONS
    • FUTURE RESEARCH
    • ACKNOWLEDGMENTS
    • REFERENCES
  • USAID Approaches to Engineering Innovation and Disaster Relief
    MARISSA JABLONSKI.
    • (1) EXAMPLES OF FUNDING OPPORTUNITIES THAT SUPPORT PARTNERSHIPS BETWEEN US AND OVERSEAS INSTITUTIONS
    • (2) CO-CREATION PROCESSES FOR APPLICANTS TO WORK WITH USAID ON MULTIPARTY ACTIVITY DESIGN
    • (3) OFFICES THAT USE ENGINEERING INNOVATION IN DISASTER RESPONSE
    • CONCLUSION
• RESILIENT AND RELIABLE INFRASTRUCTURE
  • Resilient and Reliable Infrastructure
    JULIE PIETRZAK and IRIS TIEN.
  • Communicating Advanced Infrastructure Resiliency Analytics to Diverse Groups of Stakeholders
    JOSH VERTALKA.
    • INTRODUCTION
    • THE CYNEFIN FRAMEWORK
    • THE NEED FOR BETTER DECISION SUPPORT TOOLS IN AN ERA OF ADVANCED RESEARCH
    • USER-CENTRIC APPROACH TO RESILIENCY TOOLS THROUGH CONTEXT BUILDING
    • CONCLUSIONS
    • REFERENCES
  • Climate Change and Infrastructure Resilience
    FIRAS SALEH.
    • INTRODUCTION
    • USE CASE: DAMS AND STORM EVENTS
    • DISCUSSION AND CONCLUSION
    • REFERENCES
• THERANOSTICS
  • Theranostics
    REBEKAH DREZEK and DARRELL IRVINE.
  • Developing Targeted Theranostic Nanoparticles: Challenges and Potential Solutions
    ANDREW TSOURKAS.
    • INTRODUCTION
    • ADVANTAGES AND CHALLENGES OF NANOPARTICLE DRUG DELIVERY
    • THERANOSTIC TARGETING
    • CHALLENGES AND SOLUTIONS FOR TARGETING STRATEGIES
    • PROSPECTS
    • ACKNOWLEDGMENTS
    • REFERENCES
  • Synthetic Biomarkers for Cancer Detection and Diagnosis
    ESTER J. KWON.
    • HETEROGENEITY DRIVES CHALLENGES IN CANCER TREATMENT
    • CANCER BIOMARKERS CAN GUIDE CLINICAL CARE
    • ACTIVITY-BASED NANOSENSORS AS THERANOSTICS
    • CONCLUSIONS
    • REFERENCES
  • Immune Theranostics
    EVAN A. SCOTT.
    • BACKGROUND
    • A NEW FRONTIER FOR ENGINEERING: RATIONAL IMMUNOMODULATION
    • PREVIOUS METHODS OF VACCINE DEVELOPMENT: TREATING THE IMMUNE SYSTEM AS A BLACK BOX
    • ENGINEERING NANOBIOMATERIALS FOR TARGETED IMMUNOMODULATION
    • THERANOSTICS AS A TOOL TO IMPROVE VACCINE DESIGN AND REPRODUCIBILITY
    • ENGINEERING NBMS FOR USE WITH DIAGNOSTIC IMAGING
    • CONCLUSIONS AND FUTURE DIRECTIONS
    • REFERENCES
• APPENDIXES
  • Contributors
  • Participants
  • Program

NOTICE: Publication of signed work signifies that it is judged a competent and useful contribution worthy of public consideration, but it does not imply endorsement of conclusions or recommendations by the National Academy of Engineering (NAE). The interpretations and conclusions in such publications are those of the authors and do not purport to represent the views of the council, officers, or staff of the NAE.