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Hartmann KE, Fonnesbeck C, Surawicz T, et al. Management of Uterine Fibroids [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2017 Dec. (Comparative Effectiveness Review, No. 195.)

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Management of Uterine Fibroids [Internet].

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Appendix DReasons for Exclusion

Table D-1Reasons for exclusion: Key Question 1 (n = 1,192*)

Exclusion CodeExclusion ReasonCount
X-1Does not include an intervention or treatment for uterine fibroids555
Basic science (X-1a)
Genetics/etiology (X-1b)
Imaging/diagnosis (X-1c)
Pathophysiology/physiology (X-1d)
Pre-operative adjuncts to shrink fibroids or improve anemia (X-1e)
Risk factors (X-1f)
Case report (X-1g)
Other (X-1h)
Not uterine fibroid (X-1i)
X-2Not original research548
X-3Not an eligible study design493
Prospective or retrospective cohort study (X-3a)
Non-randomized trial (X-3b)
Case series (X-3c)
Case report (X-3d)
Case-control (X-3e)
Other (X-3f)
X-4Not conducted in an eligible country36
X-5Population is not women with uterine fibroids or does not report data separately from mixed population54
X-6Does not report an outcome of interest112
X-7Does not address a Key Question162
X-10Unavailable1
X-11Non-English107
X-12Duplicate6
*

Total count exceeds number of records as records can be excluded for more than one reason

1.
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2.
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3.
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4.
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5.
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6.
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7.
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8.
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9.
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10.
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11.
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12.
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13.
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14.
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15.
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16.
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17.
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19.
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20.
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21.
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22.
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23.
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24.
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25.
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26.
Coutinho EM, Boulanger GA, Goncalves MT. Regression of uterine leiomyomas after treatment with gestrinone, an antiestrogen, antiprogesterone. Am J Obstet Gynecol. 1986 Oct;155(4):761–7. PMID: 3532799. X-3, X-3f, X-7 [PubMed: 3532799]
27.
Fakhr M, Abou-salem AM, El Sayed L, et al. Ovarian structure in cases of primary and secondary infertility. Med J Cairo Univ. 1986;54(3):423–8. PMID: 12295113. X-1, X-1d, X-1h, X-1i [PubMed: 12295113]
28.
Finikiotis G. Hysteroscopy in infertility. Clin Reprod Fertil. 1986 Aug;4(4):241–51. PMID: 3779580. X-2 [PubMed: 3779580]
29.
Gonzalez Calzada GJ. [Isthmic-cervical myomatosis as a surgical problem]. Ginecol Obstet Mex. 1986 Jul;54:176–80. PMID: 3744092. X-11 [PubMed: 3744092]
30.
Gorodeski IG, Geier A, Beery R, et al. Characterization of the nuclear progesterone receptor in human uterine leiomyoma. Eur J Obstet Gynecol Reprod Biol. 1986 Oct;23(1–2):91–9. PMID: 3023156. X-1, X-1a [PubMed: 3023156]
31.
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32.
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33.
Healy DL, Lawson SR, Abbott M, et al. Toward removing uterine fibroids without surgery: subcutaneous infusion of a luteinizing hormone-releasing hormone agonist commencing in the luteal phase. J Clin Endocrinol Metab. 1986 Sep;63(3):619–25. doi: 10.1210/jcem-63-3-619. PMID: 3090092. X-1, X-1e, X-3, X-3c [PubMed: 3090092] [CrossRef]
34.
Heidenreich W, Mlasowsky B. [Spontaneous splenic rupture as a cause of postoperative hemorrhage]. Geburtshilfe Frauenheilkd. 1986 Dec;46(12):910–1. doi: 10.1055/s-2008-1036345. PMID: 3817412. X-1, X-1i, X-3, X-3d [PubMed: 3817412] [CrossRef]
35.
Hohl MK. [Function-preserving and function-restoring operations in gynecology]. Schweiz Rundsch Med Prax. 1986 Apr 22;75(17):472–8. PMID: 3520751. X-2, X-11 [PubMed: 3520751]
36.
Hothorn W. [Invagination ileus as an acute disease picture--also in the adult]. Z Arztl Fortbild (Jena). 1986;80(19):815–8. PMID: 3811417. X-1, X-1h, X-1i, X-2 [PubMed: 3811417]
37.
Ivanescu V. [Gynecological hemorrhage in elderly women]. Rev Fr Gynecol Obstet. 1986 Nov;81(11):639–42. PMID: 3797944. X-11 [PubMed: 3797944]
38.
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39.
Landekhovskii Iu D. [Hormonal therapy and uterine steroid receptors in myoma]. Akush Ginekol (Mosk). 1986 Feb(2):10–4. PMID: 2939738. X-1, X-1b, X-1d, X-11 [PubMed: 2939738]
40.
Maheux R, Lemay A. Uterine leiomyoma: treatment with LHRH agonist. Prog Clin Biol Res. 1986;225:297–311. PMID: 3097669. X-2 [PubMed: 3097669]
41.
Makarainen L, Ylikorkala O. Primary and myoma-associated menorrhagia: role of prostaglandins and effects of ibuprofen. Br J Obstet Gynaecol. 1986 Sep;93(9):974–8. PMID: 3533137. X-1, X-1h, X-3, X-3f, X-5, X-7 [PubMed: 3533137]
42.
McLachlan RI, Healy DL, Burger HG. Clinical aspects of LHRH analogues in gynaecology: a review. Br J Obstet Gynaecol. 1986 May;93(5):431–54. PMID: 3085705. X-2 [PubMed: 3085705]
43.
Mori T, Fujii S, Konishi I. [Pathogenesis and conservative therapy of uterine leiomyoma]. Nihon Sanka Fujinka Gakkai Zasshi. 1986 Jul;38(7):1144–9. PMID: 3091738. X-2, X-11 [PubMed: 3091738]
44.
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45.
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46.
Savchenko VF, Makatsariia AD, Mishchenko AL, et al. [Evaluation of the indicators of the hemostasis system during heparin use in the prevention of postoperative thrombotic complications in gynecologic patients]. Akush Ginekol (Mosk). 1986 Sep(9):34–6. PMID: 2947493. X-1, X-11 [PubMed: 2947493]
47.
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48.
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49.
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50.
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51.
Takahashi K. [Operation of functional maintenance in myoma uteri]. Nihon Sanka Fujinka Gakkai Zasshi. 1986 Jun;38(6):971–5. PMID: 3525705. X-11 [PubMed: 3525705]
52.
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53.
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54.
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55.
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56.
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57.
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58.
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59.
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60.
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61.
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62.
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63.
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64.
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65.
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66.
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67.
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68.
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69.
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70.
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71.
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72.
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73.
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74.
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75.
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76.
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77.
Lin BL, Iwata Y, Miyamoto N, et al. Three-contrasts method: an ultrasound technique for monitoring transcervical operations. Am J Obstet Gynecol. 1987 Feb;156(2):469–72. PMID: 3548374. X-2, X-3, X-3a, X-3c, X-3f, X-7 [PubMed: 3548374]
78.
Lumsden MA, West CP, Baird DT. Goserelin therapy before surgery for uterine fibroids. Lancet. 1987 Jan 3;1(8523):36–7. PMID: 2879106. X-1, X-1e, X-2, X-3, X-3a [PubMed: 2879106]
79.
Magurno G. [Complementary sacral colpopexy]. Minerva Ginecol. 1987 Jan-Feb;39(1–2):69–75. PMID: 3574750. X-1, X-1h, X-1i [PubMed: 3574750]
80.
Maheux R, Lemay A, Merat P. Use of intranasal luteinizing hormone-releasing hormone agonist in uterine leiomyomas. Fertil Steril. 1987 Feb;47(2):229–33. PMID: 3102282. X-3, X-3c, X-3f [PubMed: 3102282]
81.
Nardelli GB, Mega M, Bertasi M, et al. Estradiol and progesterone binding in uterine leiomyomata and pregnant myometrium. Clin Exp Obstet Gynecol. 1987;14(3–4):155–60. PMID: 3454723. X-1, X-1a, X-1d [PubMed: 3454723]
82.
Perl V, Marquez J, Schally AV, et al. Treatment of leiomyomata uteri with DTrp6-luteinizing hormone-releasing hormone. Fertil Steril. 1987 Sep;48(3):383–9. PMID: 2957235. X-3, X-3c, X-3f [PubMed: 2957235]
83.
Reyniak JV, Corenthal L. Microsurgical laser technique for abdominal myomectomy. Microsurgery. 1987;8(2):92–8. PMID: 2957563. X-3, X-3c [PubMed: 2957563]
84.
Sasaki S. [Gynecological surgery: the importance of preoperative processes]. Josanpu Zasshi. 1987 Sep;41(9):730–7. PMID: 3682317. X-2, X-11 [PubMed: 3682317]
85.
Shindo K, Oikawa N, Chida S, et al. [Pharmacokinetic and clinical studies on latamoxef in the field of obstetrics and gynecology]. Jpn J Antibiot. 1987 Jul;40(7):1243–52. PMID: 3682179. X-1, X-1h, X-1i, X-3, X-3c, X-3f [PubMed: 3682179]
86.
Tyszka JJ, Stypulkowski TA, Bieniawska M. [Leiomyoma diagnosed and treated as a ganglion]. Chir Narzadow Ruchu Ortop Pol. 1987;52(5):402–4. PMID: 3454312. X-1, X-1g, X-3, X-3d [PubMed: 3454312]
87.
Vikhliaeva EM. [Conservative treatment of patients with uterine myoma]. Akush Ginekol (Mosk). 1987 Nov(11):63–7. PMID: 3439575. X-11 [PubMed: 3439575]
88.
Wang YF, Tang MY, Han ML, et al. [Ultrastructural changes in smooth muscle cells in leiomyoma and the myometrium of the human uterus after gossypol treatment]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1987 Aug;9(4):298–301. PMID: 2964936. X-1, X-1a, X-1d [PubMed: 2964936]
89.
Zhao HF. [Nailfold microcirculation in uterine myoma. Analysis of 61 cases]. Zhong Xi Yi Jie He Za Zhi. 1987 Feb;7(2):86–8, 69. PMID: 3621378. X-1, X-1h, X-3, X-3c [PubMed: 3621378]
90.
Andreyko JL, Blumenfeld Z, Marshall LA, et al. Use of an agonistic analog of gonadotropin-releasing hormone (nafarelin) to treat leiomyomas: assessment by magnetic resonance imaging. Am J Obstet Gynecol. 1988 Apr;158(4):903–10. PMID: 2966587. X-3, X-3a, X-3c [PubMed: 2966587]
91.
Baird DT, West CP. Medical management of fibroids. Br Med J (Clin Res Ed). 1988 Jun 18;296(6638):1684–5. PMID: 3135875. X-2 [PMC free article: PMC2546081] [PubMed: 3135875]
92.
Bartfai G. Clinical applications of gonadotrophin-releasing hormone and its analogues. Hum Reprod. 1988 Jan;3(1):51–7. PMID: 3280595. X-2 [PubMed: 3280595]
93.
Ben-Baruch G, Schiff E, Menashe Y, et al. Immediate and late outcome of vaginal myomectomy for prolapsed pedunculated submucous myoma. Obstet Gynecol. 1988 Dec;72(6):858–61. PMID: 3186093. X-2, X-3, X-3c [PubMed: 3186093]
94.
Bertrand de Nully M, Nielsen KD, Lykkesfeldt G. [Torsion of the non-pregnant uterus]. Ugeskr Laeger. 1988 Apr 18;150(16):983. PMID: 3376225. X-1, X-1h, X-1i [PubMed: 3376225]
95.
Chong RK, Thong PH, Tan SL, et al. Myomectomy: indications, results of surgery and relation to fertility. Singapore Med J. 1988 Feb;29(1):35–7. PMID: 3406762. X-3, X-3a, X-3f [PubMed: 3406762]
96.
Dadak C, Feiks A. [Organ-sparing surgery of leiomyomas of the uterus in young females]. Zentralbl Gynakol. 1988;110(2):102–6. PMID: 3364058. X-3, X-3c, X-3f [PubMed: 3364058]
97.
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Angioni S, Pontis A, Multinu A, et al. Safe endobag morcellation in a single-port laparoscopy subtotal hysterectomy. Minim Invasive Ther Allied Technol. 2016 Apr;25(2):113–6. doi: 10.3109/13645706.2015.1109521. PMID: 26902985. X-1, X-1g, X-3, X-3d [PubMed: 26902985] [CrossRef]
1172.
Bartels CB, Cayton KC, Chuong FS, et al. An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review. Clin Obstet Gynecol. 2016 Mar;59(1):30–52. doi: 10.1097/grf.0000000000000171. PMID: 26756261. X-2, X-3, X-3f [PubMed: 26756261] [CrossRef]
1173.
Bing-Song Z, Jing Z, Zhi-Yu H, et al. Unplanned pregnancy after ultrasound-guided percutaneous microwave ablation of uterine fibroids: A follow-up study. Sci Rep. 2016;6:18924. doi: 10.1038/srep18924. PMID: 26733265. X-3, X-3c [PMC free article: PMC4702107] [PubMed: 26733265] [CrossRef]
1174.
Bogani G, Chiappa V, Ditto A, et al. Morcellation of apparent benign uterine myoma: assessing risk to benefit ratio. J Gynecol Oncol. 2016 Apr 5:e37. doi: 10.3802/jgo.2016.27.e37. PMID: 27102246. X-2 [PMC free article: PMC4864513] [PubMed: 27102246] [CrossRef]
1175.
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1176.
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1177.
Ferrero S, Racca A, Tafi E, et al. Ulipristal Acetate Before High Complexity Hysteroscopic Myomectomy: A Retrospective Comparative Study. J Minim Invasive Gynecol. 2016 Mar-Apr;23(3):390–5. doi: 10.1016/j.jmig.2015.12.002. PMID: 26707918. X-3, X-3a [PubMed: 26707918] [CrossRef]
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1179.
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1180.
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1181.
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1182.
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1183.
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1184.
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1185.
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1186.
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1190.
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1191.
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1192.
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Table D-2Reasons for exclusion: Key Question 3 (n = 539*)

Exclusion CodeExclusion ReasonCount*
X-1Not original research178
X-2Not women with fibroids127
X-3Does not report the histopathological status of tumors from all women treated for uterine fibroids313
X-4Does not include at least 5 patients173
X-13Non-english1
X-14Published before 20144
*

Total count exceeds number of records as records can be excluded for more than one reason

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538.
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550.
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Table D-3Reasons for exclusion: Key Question 4 (n = 979*)

Exclusion CodeExclusion ReasonCount*
L1: X-1; L2: X-1Not original research272
L1: X-2Not women with fibroids345
L1: X-3; L2: X-4Does not include at least patients treated for uterine fibroids491
L1: X-4; L2: X-2Does not report method for tissue removal200
L1: X-5; L2: X-5Does not report outcome(s) related to leiomyosarcoma subsequent to treatment for uterine fibroids584
L2: X-3Ineligible study design or article type9
L2: X-10Unavailable1
L2: X-11Non-English1
*

Total count exceeds number of records as records can be excluded for more than one reason

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