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Balk E, Adam GP, Kimmel H, et al. Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 Aug. (Comparative Effectiveness Review, No. 212.)
Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update [Internet].
Show detailsTable 21Quality of life outcomes for pharmacological versus pharmacological interventions
| Intervention A | Intervention B | Bother | Daily Activities | Distress | General Health | Mental Health | Pain | Sexual Health | Sleep/Energy | |
|---|---|---|---|---|---|---|---|---|---|---|
| Anticholinergic vs. anticholinergic | Oxybutynin | Tolterodine | 1 (90): 1 NS | 1 (90): 1 NS | ||||||
| Oxybutynin | Trospium chloride | 1 (90): 1 NS | 1 (90): 1 NS | |||||||
| Oxybutynin 2.6 mg | Oxybutynin 3.9 mg | 1 (254): 1 favor† B | ||||||||
| Solifenacin | Darifenacin | 1 (76): 1 NS | 1 (76): 1 disc | |||||||
| Anticholinergic vs. onabotulinum toxin A | Solifenacin | Onabotulinum toxin A | 1 (247): 1 NS | |||||||
| Anticholinergic vs. anticholinergic and hormonal therapy | Fesoterodine | Fesoterodine, vaginal estrogen | 1 (18): 1 NS | 1 (18): 1 NS | ||||||
| Anticholinergic vs. antiepileptic | Tolterodine | Pregabalin | 1 (178): 1 NS | |||||||
| Tolterodine + pregabalin | Pregabalin | 1 (178): 1 NS |
Empty cells indicate that the intervention was not evaluated for the outcome designated in the given column
Abbreviations: disc = discordant findings; NS = non-significant.
- *
Results are given as number of studies (number of people), number of studies with significant difference and which intervention it favors, number of studies with discordant results (that is, within the same study, significant differences favoring one intervention were found on one scale or subscale, but nonsignificant differences were found on others, number of studies with nonsignificant differences.
- †
Favor indicates a statistically significant (net) difference favoring the specified intervention.
- Table 21, Quality of life outcomes for pharmacological versus pharmacological in...Table 21, Quality of life outcomes for pharmacological versus pharmacological interventions - Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update
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