FIGURE 18.1. Dysregulation of metabolic pathways during ischaemia.

FIGURE 18.1Dysregulation of metabolic pathways during ischaemia

Anaerobic glycolysis during ischaemia results in negative feedback which inhibits ATP production, thereby inducing tissue acidosis, calcium influx and tissue oedema.

From: 18, Pathophysiology of Reperfusion Injury

Cover of Mechanisms of Vascular Disease
Mechanisms of Vascular Disease: A Reference Book for Vascular Specialists [Internet].
Fitridge R, Thompson M, editors.
Adelaide (AU): University of Adelaide Press; 2011.
© The Contributors 2011.

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