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Clinical Review Report: Netupitant/Palonosetron 300 mg/0.5 mg (Akynzeo): (Purdue Pharma): Indication: In combination with dexamethasone, once-per-cycle treatment for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cancer chemotherapy, or with moderately emetogenic cancer chemotherapy that is uncontrolled by a 5-hydroxytryptamine-3 receptor antagonist alone [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2018 Jun.

Cover of Clinical Review Report: Netupitant/Palonosetron 300 mg/0.5 mg (Akynzeo)

Clinical Review Report: Netupitant/Palonosetron 300 mg/0.5 mg (Akynzeo): (Purdue Pharma): Indication: In combination with dexamethasone, once-per-cycle treatment for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cancer chemotherapy, or with moderately emetogenic cancer chemotherapy that is uncontrolled by a 5-hydroxytryptamine-3 receptor antagonist alone [Internet].

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Figure 26. Network for Total Control: Highly Emetogenic Chemotherapy and Anthracycline/Cyclophosphamide — Acute Phase.

Figure 26Network for Total Control: Highly Emetogenic Chemotherapy and Anthracycline/Cyclophosphamide — Acute Phase

APR = aprepitant; DEX = dexamethasone; FOS = fosaprepitant; GRA = granisetron; NET = netupitant; OND = ondansetron; PAL = palonosetron.

Source: NEPA MTC report.45

From: Appendix 6, Summary of Mixed-Treatment Comparisons

Copyright © 2018 Canadian Agency for Drugs and Technologies in Health.

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