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Guidelines for the Care and Treatment of Persons Diagnosed with Chronic Hepatitis C Virus Infection [Internet]. Geneva: World Health Organization; 2018 Jul.

Cover of Guidelines for the Care and Treatment of Persons Diagnosed with Chronic Hepatitis C Virus Infection

Guidelines for the Care and Treatment of Persons Diagnosed with Chronic Hepatitis C Virus Infection [Internet].

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Abbreviations and Acronyms

AASLD

American Association for the Study of Liver Disease

Ab

antibody

AE

adverse event

ALT

alanine aminotransferase

anti-HBc

antibody to hepatitis B core antigen

APRI

AST-to-platelet ratio index

ART

antiretroviral therapy

ARV

antiretroviral

AST

aspartate aminotransferase

CI

confidence interval

DAA

direct-acting antiviral (medicine)

DBS

dried blood spot

DDI

drug–drug interaction

EASL

European Association for the Study of the Liver

eGFR

estimated glomerular filtration rate

EMA

European Medicines Agency

FBC

full blood count

FDA

United States Food and Drug Administration

FDC

fixed-dose combination

FIB-4

fibrosis-4 index for liver fibrosis

GHP

Global Hepatitis Programme

GHSS

Global Health Sector Strategy (on viral hepatitis)

GRADE

Grading of Recommendations Assessment, Development and Evaluation

HBsAg

hepatitis B surface antigen

HBV

hepatitis B virus

HCC

hepatocellular carcinoma

HCV

hepatitis C virus

HIC

high-income country

HIV

human immunodeficiency virus

LMICs

low- and middle-income countries

MSF

Médecins Sans Frontières or Doctors Without Borders

MSM

men who have sex with men

NAT

nucleic acid testing/test

NS5B

non-structural protein 5B (of HCV)

NS3/NS4A

non-structural protein 3/non-structural protein 4A (of HCV)

NSP

needle–syringe programme

OR

odds ratio

OST

opioid substitution therapy

PEG-IFN

pegylated interferon

PICO

Population, Intervention, Comparison, Outcomes

PWID

people who inject drugs

RBV

ribavirin

RCT

randomized controlled trial

RDT

rapid diagnostic test

RNA

ribonucleic acid

RR

relative risk

SAE

severe adverse event

STI

sexually transmitted infection

SVR12

sustained virological response at 12 weeks post-treatment

TB

tuberculosis

UK

United Kingdom

USA

United States of America

WHO

World Health Organization

WTO

World Trade Organization

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Bookshelf ID: NBK531724

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