Figure 1.2Fluctuation analysis of currents stimulated by thapsigargin in Jurkat T cells.

a. Macroscopic Ca2+ current (upper) and variance (lower) elicited by 1 μM thapsigargin.

a

Macroscopic Ca2+ current (upper) and variance (lower) elicited by 1 μM thapsigargin.

b. Variance plotted against mean current for the data from (a).

b

Variance plotted against mean current for the data from (a). Linear regression fits are superimposed on the data collected in 2 and 110 mM (Ca2+)o. Unitary current amplitudes are -1.3 fA (2 mM Ca2+) and -2.9 fA (110 mM Ca2+), as indicated by the slopes. (more...)

(Reproduced from Zweifach, A. and Lewis, R.S., Proc. Natl. Acad. Sci. USA, 90, 6295, 1993, Figure 3.)

From: Chapter 1, Electrophysiological Methods for Recording CRAC and TRPV5/6 Channels

Cover of Calcium Entry Channels in Non-Excitable Cells
Calcium Entry Channels in Non-Excitable Cells.
Kozak JA, Putney JW Jr., editors.
Boca Raton (FL): CRC Press/Taylor & Francis; 2018.
© 2017 by Taylor & Francis Group, LLC.

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