© 2017 by Taylor & Francis Group, LLC.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
< PrevNext >
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Calcium Entry Channels in Non-Excitable Cells
Editors
Editors: Juliusz Ashot Kozak and James W. Putney, Jr.Boca Raton (FL): CRC Press/Taylor & Francis; 2018.
ISBN-13: 9781498752725 (hardback)ISBN-13: 9781315152592 (ebook)
© 2017 by Taylor & Francis Group, LLC.
Contents
- Series Preface
- Preface
- 1. Electrophysiological Methods for Recording CRAC and TRPV5/6 ChannelsJ. Ashot Kozak and Grigori Rychkov.
- 2. Studies of Structure-Function and Subunit Composition of Orai/STIM ChannelMarc Fahrner, Rainer Schindl, and Christoph Romanin.
- 3. Signaling ER Store Depletion to Plasma Membrane Orai ChannelsAparna Gudlur and Patrick Hogan.
- 4. Modulation of Orai1 and STIM1 by Cellular FactorsJin Seok Woo, Sonal Srikanth, and Yousang Gwack.
- 4.1. Introduction
- 4.2. Modulators of Orai1 via Protein Interaction
- 4.3. Vesicular Components in Regulation of Orai1
- 4.4. Store-Independent Regulation of Orai1 via Protein Interaction
- 4.5. STIM1-Interacting Molecules at the ER-PM Junctions
- 4.6. Modulators of STIM1 Function
- 4.7. STIM1 as a Regulator for Non-CRAC Channel-Related Functions
- 4.8. Methods Used to Identify Interacting Partners of Orai1 and STIM1
- 4.9. Conclusions and Perspectives
- Acknowledgments
- References
- 5. CRAC Channels and Ca2+-Dependent Gene ExpressionYi-Chun Yeh and Anant B. Parekh.
- 5.1. Introduction
- 5.2. Ca2+ Entry through CRAC Channels Activates Gene Expression
- 5.3. The Importance of Ca2+ Microdomains near Open CRAC Channels in the Regulation of Transcription
- 5.4. How Local Is Local?
- 5.5. Sensing Local Ca2+ near CRAC Channels
- 5.6. Parallel Processing of the CRAC Channel Ca2+ Microdomain
- 5.7. Caveolin-1 Differentially Regulates NFAT and c-Fos Activities
- 5.8. Modular Regulation by Caveolin-1
- 5.9. Large Bulk Ca2+ Rises and c-Fos Gene Expression
- 5.10. Conclusion
- References
- 6. Function of Orai/Stim Proteins Studied in Transgenic Animal ModelsMasatsugu Oh-Hora and Xiuyuan Lu.
- 6.1. Introduction
- 6.2. Strategies for Gene Targeting
- 6.3. Establishment of Orai/Stim-Deficient Mice at the Whole-Body Level
- 6.4. Establishment of Tissue-Specific Orai/Stim-Deficient Mouse Lines
- 6.5. Methods to Establish Murine Embryonic Fibroblast Lines from KO Mice
- 6.6. Function of Orai/Stim Proteins in the Immune System
- 6.7. Function of Orai/Stim Proteins in the Muscle
- 6.8. Function of Orai/Stim Proteins in the Nervous System
- 6.9. Concluding Remarks
- Acknowledgments
- References
- 7. Assessing the Molecular Nature of the STIM1/Orai1 Coupling Interface Using FRET ApproachesYandong Zhou, Youjun Wang, and Donald L. Gill.
- 8. Optogenetic Approaches to Control Calcium Entry in Non-Excitable CellsLian He, Qian Zhang, Yubin Zhou, and Yun Huang.
- 9. Regulation of Orai/STIM Channels by pHAlbert S. Yu, Zhichao Yue, Jianlin Feng, and Lixia Yue.
- 10. Non-Orai Partners of STIM Proteins: Role in ER-PM Communication and Ca2+ SignalingKlaus Groschner, Niroj Shrestha, and Nicola Fameli.
- 11. Store-Independent Orai Channels Regulated by STIMXuexin Zhang, Maxime Gueguinou, and Mohamed Trebak.
- 12. Regulation and Role of Store-Operated Ca2+ Entry in Cellular ProliferationRawad Hodeify, Fang Yu, Raphael Courjaret, Nancy Nader, Maya Dib, Lu Sun, Ethel Adap, Satanay Hubrack, and Khaled Machaca.
- 13. TRPV5 and TRPV6 Calcium-Selective ChannelsJi-Bin Peng, Yoshiro Suzuki, Gergely Gyimesi, and Matthias A. Hediger.
- 13.1. Introduction
- 13.2. Ca2+ Transport across Epithelia
- 13.3. Identification of TRPV5 and TRPV6 by Expression Cloning
- 13.4. Ca2+ Transport Properties Uncovered by Various Approaches
- 13.5. Physiological Roles Revealed Using Genetically Engineered Animal Models
- 13.6. Proteins that Regulate TRPV5 and TRPV6
- 13.7. Potential Use of TRPV6 in Therapy and Development of Chemical Modulators
- 13.8. TRPV5 and TRPV6 Mutations and Kidney Stone Diseases
- 13.9. Concluding Remarks
- Acknowledgments
- References
- 14. Determining the Crystal Structure of TRPV6Kei Saotome, Appu K. Singh, and Alexander I. Sobolevsky.
- 14.1. Introduction
- 14.2. Precrystallization Screening of Protein Expression and Biochemical Behavior Using FSEC
- 14.3. Large-Scale Purification and Crystallization
- 14.4. Collection and Processing of Diffraction Data
- 14.5. Protein Engineering to Improve Crystal Packing
- 14.6. Comparison of TRPV6 and Orai Structures
- Acknowledgments
- References
- 15. Identifying TRP Channel Subunit Stoichiometry Using Combined Single Channel Single Molecule Determinations (SC-SMD)Laura G. Ceballos, Alexander Asanov, and Luis Vaca.
- 16. Pharmacology of Store-Operated Calcium Entry ChannelsGary S. Bird and James W. Putney, Jr.
CRC Press
Taylor & Francis Group
6000 Broken Sound Parkway NW, Suite 300
Boca Raton, FL 33487-2742
CRC Press is an imprint of Taylor & Francis Group, an Informa business
No claim to original U.S. Government works
Printed on acid-free paper
This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint.
Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers.
For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged.
Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe.
Names: Kozak, Juliusz Ashot, editor. | Putney, James W., Jr., editor.
Title: Calcium entry channels in non-excitable cells / [edited by] Juliusz
Ashot Kozak and James W. Putney, Jr.
Other titles: Methods in signal transduction.
Description: Boca Raton : Taylor & Francis, 2017. | Series: Methods in signal transduction series | Includes bibliographical references and index.
Identifiers: LCCN 2016053681 | ISBN 9781498752725 (hardback : alk. paper)
Subjects: | MESH: Calcium Channels--physiology | Calcium Signaling--physiology
Classification: LCC QP552.C24 | NLM QU 55.7 | DDC 572/.696--dc23
LC record available at https://lccn.loc.gov/2016053681
Visit the Taylor & Francis Web site at
http://www.taylorandfrancis.com
and the CRC Press Web site at
SPiGlobal