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Forman-Hoffman V, Middleton JC, Feltner C, et al. Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 May. (Comparative Effectiveness Review, No. 207.)
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Show detailsTable G-4Characteristics of mixed intervention trials omitted from main analyses because of high risk of bias
| Trial | Arm (N) | Treatment Duration (Followup Post Treatment) | Population Trauma Type | Baseline PTSD Severity | Mean Age (Y) | % Female % Nonwhite |
|---|---|---|---|---|---|---|
| Beck et al., 2009200 | CBT-M (17) MCC (16) | 14 weeks (3 months) | Male and female MVA | 57.3 to 57.8 | 43 | 82 11 |
| Beidel et al., 2011201 | CBT-M (18) Exposure (17) | 17 weeks | Male Combat | 84.9 to 90.6 | 59 | 0 0 |
| Difede et al., 2007206 | CBT-M (15) Usual care (16) | 12 weeks (12 to 13 weeks) | Disaster workers World Trade Center attack | 50.5 to 51.7 | 46 | 3 23 |
| Dorrepaal et al., 2012207 | CBT-M (“Stabilitizing group treatment”) (38) Usual care (33) | 20 weeks (post) | Complex PTSD and severe comorbidity | DTS 80 to 90 | 39 | NR NR |
| Dunne et al., 2012208 | TF-CBT (13) Waitlist (13) | 10 weeks (post) | MVC-related PTSD (specifically WAD) | PDS 21 to 23 | 32 | 50 NR |
| Echeburua et al., 1996263 | CBT-M (10) CBT Cope (10) | 5 weeks (1, 3, 6, and 12 months) | Female Sexual assault | NR | 22 | 100 NR |
| Lee et al., 2002227 | EMDR (12) CBT-Mb (SIT+PE) (12) | 7 weeks (3 months) | Male and female Mixed | IES 55.3 | 35 | 46 NR |
| Littleton et al., 2016229 | Interactive online therapist-facilitated CBT (46) Psychoeducation self-help website (41) | 14 weeks (post, 3 months) | Rape related PTSD | PSS-I 23 to 23.7 | 22 | 100 47 |
| Mueser et al., 2015234 | CBT for PTSD (104) Brief treatment (97) | 12 to 16 weeks (post, 6 months, 12 months) | PTSD and severe mental illness | 85.76 to 86.06 | 44 | 69 66 |
| Margolies et al., 2013231 | CBTI plus IRT (20) Waitlist (20) | 4 sessions over 6 weeks (post collected 2 weeks after 6 week treatment period) | Combat Veterans | PSS-SR 39.8 to 41.8 | 38 | 10 60 |
| Paunovic et al., 2001239 | Exposure (10) CBT-M (10) | 16 to 20 weeks (6 months) | Male and female Refugees | 95.1 to 98.4 | 38 | 15 NR |
| Polak et al., 2015247 | TF-CBT plus breathing biofeedback (4) TF-CBT (4) | 5 to 18 sessions (post) | Chronic PTSD Mixed | IES-R 41.5 to 45 | 45 | 75 NR |
| Power et al., 2002243 | EMDR (39) CBT-Ma (Exp+CR) (37) Waitlist (29) | 10 weeks | Male and female Mixed | IES 32.6 to 35.1 | 39 | 42 NR |
| Stecker et al., 2014251 | Brief CBT (123) Usual care (151) | 1 session (1 month, 3 months, 6 months) | Veterans of Iraq war with PTSD | PTSD Checklist 59.2 to 59.7 | 29 | 13 31 |
| Ulmer et al., 2011254 | CBT-M (12) Usual care (9) | 6 biweekly sessions, over 12 weeks | Male and female Recently deployed veterans | PCL-M 63.1 to 63.4 | 46 | 31.8 66.6 |
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The information provided after CBT-M indicates the content of the mixed intervention (see abbreviations below).
CBT Cope = cognitive behavioral therapy-coping skills; CBT-M = cognitive behavioral therapy-mixed; CR = cognitive restructuring; EMDR = eye movement desensitization and reprocessing; exp = exposure therapy; IES = Impact of Event Scale; MCC = minimum contact comparison group; NR = not reported; PCL-M = PTSD Checklist-Military Version; PE = prolonged exposure; relax = relaxation; SIT = stress inoculation training; y = year.
- Table G-4, Characteristics of mixed intervention trials omitted from main analys...Table G-4, Characteristics of mixed intervention trials omitted from main analyses because of high risk of bias - Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
- 83715[geneid] (489)ClinVar
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