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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
Drug Levels and Effects
Summary of Use during Lactation
Uva ursi (Arctostaphylos uva-ursi) leaves contain arbutin, which is hydrolyzed to hydroquinone. Uva ursi has no specific lactation-related uses, but is most often used as a urinary antiseptic. No data exist on the excretion of any components of uva ursi into breastmilk or on the safety and efficacy of uva ursi in nursing mothers or infants. Uva ursi should generally be avoided during breastfeeding because of a lack of data and its potential toxicity.[1,2]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
(Urinary Antiseptic) Methenamine Hippurate, Methenamine Mandelate, Nitrofurantoin
References
- 1.
- Kopec K. Herbal medications and breastfeeding. J Hum Lact 1999;15:157-61. [PubMed: 10578793]
- 2.
- Nice F, Coghlan R, Birmingham B. Which herbals are safe to take while breastfeeding? Here's a guide to popular herbs and their potential risk to nurslings. US Pharm 2000;25:1-9.
Substance Identification
Substance Name
Uva Ursi
Scientific Name
Arctostaphylos uva-ursi
Drug Class
Breast Feeding
Milk, Human
Complementary Therapies
Phytotherapy
Plants, Medicinal
Anti-Infective Agents, Urinary
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- PubMedLinks to PubMed
- Review Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations.[Int J Toxicol. 2013]Review Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations.de Arriba SG, Naser B, Nolte KU. Int J Toxicol. 2013 Nov-Dec; 32(6):442-53.
- Chemical Characteristics and Antioxidant Activity of Arctostaphylos uva-ursi L. Spreng. at the Southern Border of the Geographical Range of the Species in Europe.[Molecules. 2021]Chemical Characteristics and Antioxidant Activity of Arctostaphylos uva-ursi L. Spreng. at the Southern Border of the Geographical Range of the Species in Europe.Sugier P, Sęczyk Ł, Sugier D, Krawczyk R, Wójcik M, Czarnecka J, Okoń S, Plak A. Molecules. 2021 Dec 20; 26(24). Epub 2021 Dec 20.
- Comparative stability of arbutin in Arctostaphylos uva-ursi by a new comprehensive stability-indicating HPLC method.[Phytochem Anal. 2020]Comparative stability of arbutin in Arctostaphylos uva-ursi by a new comprehensive stability-indicating HPLC method.Braga VCC, Pianetti GA, César IC. Phytochem Anal. 2020 Nov; 31(6):884-891. Epub 2020 Jun 4.
- Proteome changes in human bladder T24 cells induced by hydroquinone derived from Arctostaphylos uva-ursi herbal preparation.[J Ethnopharmacol. 2022]Proteome changes in human bladder T24 cells induced by hydroquinone derived from Arctostaphylos uva-ursi herbal preparation.Huđek Turković A, Gunjača M, Marjanović M, Lovrić M, Butorac A, Rašić D, Peraica M, Vujčić Bok V, Šola I, Rusak G, et al. J Ethnopharmacol. 2022 May 10; 289:115092. Epub 2022 Feb 8.
- Review Bladder infection: Do herbal remedies help with recurrent bladder infection? IQWiG Reports – Commission No. HT20-01[ 2022]Review Bladder infection: Do herbal remedies help with recurrent bladder infection? IQWiG Reports – Commission No. HT20-01. 2022 Feb 24
- Uva Ursi - Drugs and Lactation Database (LactMed®)Uva Ursi - Drugs and Lactation Database (LactMed®)
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