Summary of Use during Lactation

No information is available on the use of dienogest during breastfeeding. Dienogest is only available in the United States in a combination oral contraceptive product that also contains estradiol valerate. Based on the available evidence, expert opinion holds that progestin-only contraceptives are preferred over combined oral contraceptives in breastfeeding women, especially during the first 4 weeks postpartum.[1] For further information, consult the record entitled, Contraceptives, Oral, Combined.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Etonogestrel, Intrauterine Copper Contraceptive, Oral Levonorgestrel, Intrauterine Levonorgestrel, Levonorgestrel Implant, Medroxyprogesterone Acetate, Norethindrone, Progesterone

References

1.

World Health Organization. Medical Eligibility Criteria For Contraceptive Use: Sixth Ed. 2025. https://www​.who.int/publications​/i/item/9789240115583. [PubMed: 41325508]

Substance Name

Dienogest

CAS Registry Number

65928-58-7

Drug Class

Breast Feeding

Lactation

Milk, Human

Contraceptive Agents, Female

Contraceptives, Oral, Synthetic