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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

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Drugs and Lactation Database (LactMed®) [Internet].

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Benzocaine

Last Revision: October 18, 2021.

Estimated reading time: 1 minute

CASRN: 94-09-7

image 134970801 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

Topical benzocaine has not been studied during breastfeeding, but is unlikely to affect her breastfed infant if it is applied away from the breast. Benzocaine should not be applied to the breast or nipple, because the infant may ingest the drug during nursing and it has been associated with severe methemoglobinemia in children under 2 years of age.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Lidocaine

References

1.
US Food and Drug Administration. Risk of serious and potentially fatal blood disorder prompts FDA action on oral over-the-counter benzocaine products used for teething and mouth pain and prescription local anesthetics. 2018. https://www​.fda.gov/drugs​/drug-safety-and-availability​/risk-serious-and-potentially-fatal-blood-disorder-prompts-fda-action-oral-over-counter-benzocaine.

Substance Identification

Substance Name

Benzocaine

CAS Registry Number

94-09-7

Drug Class

Breast Feeding

Lactation

Anesthetics, Local

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Copyright Notice

Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Bookshelf ID: NBK501753PMID: 30000812

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