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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

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Drugs and Lactation Database (LactMed®) [Internet].

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Zoledronic Acid

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 118072-93-8

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

Because no information is available on the use of zoledronic acid during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. However, absorption of zoledronic acid by a breastfed infant is unlikely.

Drug Levels

Zoledronic acid has a serum half-life of about 1.7 hours and is poorly absorbed orally, so absorption of zoledronic acid by a breastfed infant is unlikely.

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Pamidronate

Substance Identification

Substance Name

Zoledronic Acid

CAS Registry Number

118072-93-8

Drug Class

  • Breast Feeding
  • Bisphosphonates
  • Bone Density Conservation Agents
  • Diphosphonates

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Copyright Notice

Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Bookshelf ID: NBK501620PMID: 30000681

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