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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 29110-47-2
Drug Levels and Effects
Summary of Use during Lactation
Because no information is available on the use of guanfacine during breastfeeding and its possible negative effects on lactation, other agents may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Published information on the effects of guanfacine on serum prolactin or on lactation in nursing mothers was not found as of the revision date. Guanfacine decreases basal serum prolactin in men and nonnursing women. Serum prolactin continues to decrease for at least 7 years during continuous use.[1] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Alternate Drugs to Consider
(ADHD) Amphetamine, Dextroamphetamine, Lisdexamfetamine, Methylphenidate (Hypertension) Enalapril, Hydrochlorothiazide, Methyldopa, Propranolol
References
- 1.
- Hauger-Klevene JH, Balossi EC, Scornavacchi JC. Effects of guanfacine on growth hormone, prolactin, renin, lipoproteins and glucose in essential hypertension. Am J Cardiol. 1986;57:27E–31E. [PubMed: 3513527] [CrossRef]
Substance Identification
Substance Name
Guanfacine
CAS Registry Number
29110-47-2
Drug Class
Breast Feeding
Lactation
Milk, Human
Antihypertensive Agents
Adrenergic alpha-2 Receptor Agonists
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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