Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 8050-81-5
Drug Levels and Effects
Summary of Use during Lactation
Although no data are available on the use of simethicone during breastfeeding, it is known that simethicone is not absorbed orally. Therefore, it cannot be transferred to breastmilk. It is also used safely in breastfed infants.[1,2] No special precautions are required.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998;14:259–62. [PubMed: 10205441]
- 2.
- Savino F, Pelle E, Palumeri E, et al. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: A prospective randomized study. Pediatrics. 2007;119:e124–30. [PubMed: 17200238]
Substance Identification
Substance Name
Simethicone
CAS Registry Number
8050-81-5
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubChem SubstanceRelated PubChem Substances
- PubMedLinks to PubMed
- Review Magnesium Hydroxide.[Drugs and Lactation Database (...]Review Magnesium Hydroxide.. Drugs and Lactation Database (LactMed®). 2006
- Mylicon drops in the treatment of infant colic.[Clin Ther. 1988]Mylicon drops in the treatment of infant colic.Becker N, Lombardi P, Sidoti E, Katkin LS. Clin Ther. 1988; 10(4):401-5.
- Endotoxin inactivation via steam-heat treatment in dilute simethicone emulsions used in biopharmaceutical processes.[Biotechnol Prog. 2014]Endotoxin inactivation via steam-heat treatment in dilute simethicone emulsions used in biopharmaceutical processes.Britt KA, Galvin J, Gammell P, Nti-Gyabaah J, Boras G, Kolwyck D, Ramirez JG, Presente E, Naugle G. Biotechnol Prog. 2014 Sep-Oct; 30(5):1145-60. Epub 2014 Apr 2.
- Product recalls. Recalls: Infants' Mylicon Gas Relief Dye Free Drops...Toy Trains...and Cobra Electronics Children's Two-Way Radios sold exclusively in Toys "R" Us Stores.[Child Health Alert. 2008]Product recalls. Recalls: Infants' Mylicon Gas Relief Dye Free Drops...Toy Trains...and Cobra Electronics Children's Two-Way Radios sold exclusively in Toys "R" Us Stores.. Child Health Alert. 2008 Dec; 26:4-5.
- Review Peginterferon Beta.[Drugs and Lactation Database (...]Review Peginterferon Beta.. Drugs and Lactation Database (LactMed®). 2006
- Simethicone - Drugs and Lactation Database (LactMed®)Simethicone - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...