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Bookshelf ID: NBK501416PMID: 30000476
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 8050-81-5
Drug Levels and Effects
Summary of Use during Lactation
Although no data are available on the use of simethicone during breastfeeding, it is not absorbed orally. Therefore, it cannot be transferred to breastmilk.[1] It is also used safely given directly to infants.[2,3] No special precautions are required.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Mahadevan U, Kane S. American Gastroenterological Association Institute Technical Review on the Use of Gastrointestinal Medications in Pregnancy. Gastroenterology 2006;131:283-311 [PubMed: 16831611]
- 2.
- Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact 1998;14:259-62 [PubMed: 10205441]
- 3.
- Savino F, Pelle E, Palumeri E, et al. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: A prospective randomized study. Pediatrics 2007;119:e124-30 [PubMed: 17200238]
Substance Identification
Substance Name
Simethicone
CAS Registry Number
8050-81-5
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Product recalls. Recalls: Infants' Mylicon Gas Relief Dye Free Drops...Toy Trains...and Cobra Electronics Children's Two-Way Radios sold exclusively in Toys "R" Us Stores.[Child Health Alert. 2008]Product recalls. Recalls: Infants' Mylicon Gas Relief Dye Free Drops...Toy Trains...and Cobra Electronics Children's Two-Way Radios sold exclusively in Toys "R" Us Stores.. Child Health Alert. 2008 Dec; 26:4-5.
- Acid-neutralizing capacity and sodium content of antacid products from Belgium.[Clin Ther. 1984]Acid-neutralizing capacity and sodium content of antacid products from Belgium.Gombatz VW. Clin Ther. 1984; 6(2):151-4.
- Review Dimethicone.[Drugs and Lactation Database (...]Review Dimethicone.. Drugs and Lactation Database (LactMed®). 2006
- The effect of oral polyethylene glycol combined with simethicone for colonoscopy on cecal intubation rate, tolerability and acceptability : a systematic review and meta-analysis.[Acta Gastroenterol Belg. 2019]The effect of oral polyethylene glycol combined with simethicone for colonoscopy on cecal intubation rate, tolerability and acceptability : a systematic review and meta-analysis.Li Y, Xing S, Chen R, Zhou Z, Guo Y. Acta Gastroenterol Belg. 2019 Jul-Sep; 82(3):407-415.
- The effect of using simethicone with or without N-acetylcysteine before gastroscopy: A meta-analysis and systemic review.[Saudi J Gastroenterol. 2019]The effect of using simethicone with or without N-acetylcysteine before gastroscopy: A meta-analysis and systemic review.Li Y, Du F, Fu D. Saudi J Gastroenterol. 2019 Jul-Aug; 25(4):218-228.
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