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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

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Drugs and Lactation Database (LactMed®) [Internet].

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Amiloride

Last Revision: June 15, 2024.

CASRN: 2609-46-3

image 134981473 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the use of amiloride during breastfeeding, so an alternate drug may be preferred.

Drug Levels

Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Intense diuresis can suppress lactation;[1,2] however, it is unlikely that amiloride alone is sufficiently potent to cause this effect.

Alternate Drugs to Consider

Spironolactone

References

1.
Healy M. Suppressing lactation with oral diuretics. Lancet 1961;277(7190):1353-4. doi: 10.1016/S0140-6736(61)90289-6 [CrossRef]
2.
Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. [PubMed: 3858]

Substance Identification

Substance Name

Amiloride

CAS Registry Number

2609-46-3

Drug Class

Breast Feeding

Lactation

Milk, Human

Diuretics

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Copyright Notice

Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Bookshelf ID: NBK500950PMID: 30000009

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