Von Willebrand Factor

Publication Details

Estimated reading time: 1 minute

CASRN: 109319-16-6

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the clinical use of von Willebrand factor during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract.[1] Until more data become available, von Willebrand factor should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Stratigakis A, Paty D, Zou P, et al. A regression approach for assessing large molecular drug concentration in breast milk. Reprod Breed 2023;3:199–207. doi:10.1016/j.repbre.2023.10.003 [CrossRef]

Substance Identification

Substance Name

Von Willebrand Factor

CAS Registry Number

109319-16-6

Drug Class

Breast Feeding

Lactation

Milk, Human

Blood Coagulation Factors

Coagulants

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