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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 109319-16-6
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the clinical use of von Willebrand factor during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract.[1] Until more data become available, von Willebrand factor should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Stratigakis A, Paty D, Zou P, et al. A regression approach for assessing large molecular drug concentration in breast milk. Reprod Breed 2023;3:199–207. doi:10.1016/j.repbre.2023.10.003 [CrossRef]
Substance Identification
Substance Name
Von Willebrand Factor
CAS Registry Number
109319-16-6
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Absence of a bleeding tendency in severe acquired von Willebrand's disease. The role of platelet von Willebrand factor in maintaining normal hemostasis.[Am J Clin Pathol. 1989]Absence of a bleeding tendency in severe acquired von Willebrand's disease. The role of platelet von Willebrand factor in maintaining normal hemostasis.Drouin J, Lillicrap DP, Izaguirre CA, Sutherland M, Windsor S, Benford K, Hoogendorn H, Giles AR. Am J Clin Pathol. 1989 Oct; 92(4):471-8.
- Development of an inhibitor specific to factor VIII: coagulant activity in a patient with platelet-type von Willebrand's disease.[Am J Clin Pathol. 1983]Development of an inhibitor specific to factor VIII: coagulant activity in a patient with platelet-type von Willebrand's disease.Castella A, Miller JL, Neuberg RW, Gawryl MS, Hoyer LW. Am J Clin Pathol. 1983 Nov; 80(5):745-9.
- Diagnosis of von Willebrand's disease. A comparative study of diagnostic tests on nine families with von Willebrand's disease and its differential diagnosis from hemophilia and thrombocytopathy.[Am J Med. 1976]Diagnosis of von Willebrand's disease. A comparative study of diagnostic tests on nine families with von Willebrand's disease and its differential diagnosis from hemophilia and thrombocytopathy.Lian EC, Deykin D. Am J Med. 1976 Mar; 60(3):344-56.
- Review Von Willebrand's disease: case report and review of literature.[Pan Afr Med J. 2017]Review Von Willebrand's disease: case report and review of literature.Echahdi H, El Hasbaoui B, El Khorassani M, Agadr A, Khattab M. Pan Afr Med J. 2017; 27:147. Epub 2017 Jun 29.
- Review Factor Xa (recombinant), Inactivated.[Drugs and Lactation Database (...]Review Factor Xa (recombinant), Inactivated.. Drugs and Lactation Database (LactMed®). 2006
- Von Willebrand Factor - Drugs and Lactation Database (LactMed®)Von Willebrand Factor - Drugs and Lactation Database (LactMed®)
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