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Bookshelf ID: NBK500796PMID: 29999855
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 140709-07-5
Drug Levels and Effects
Summary of Use during Lactation
Information in this record refers to the use of rhenium-186 HEDP (rhenium-186 etidronate) as a therapeutic agent. No information is available on the therapeutic use of rhenium HEDP during breastfeeding. Because strontium can substitute for calcium in infant bones, the manufacturer and expert opinion recommend discontinuing breastfeeding before a nursing mother receives rhenium HEDP.[1]
Drug Levels
Rhenium 186 emits a beta particle with a mean energy of 0.349 MeV and gamma emission with a 0.137 MeV photo peak. Its physical half-life is 3.7 days.[1]
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Bodei L, Lam M, Chiesa C, et al. EANM procedure guideline for treatment of refractory metastatic bone pain. Eur J Nucl Med Mol Imaging 2008;35:1934-40. [PubMed: 18649080]
Substance Identification
Substance Name
Rhenium-186 HEDP
CAS Registry Number
140709-07-5
Drug Class
Breast Feeding
Lactation
Milk, Human
Radiopharmaceuticals
Etidronic Acid
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Review Etidronate.[Drugs and Lactation Database (...]Review Etidronate.. Drugs and Lactation Database (LactMed®). 2006
- Assessment of 186Re chelate-conjugated bisphosphonate for the development of new radiopharmaceuticals for bones.[Nucl Med Biol. 2007]Assessment of 186Re chelate-conjugated bisphosphonate for the development of new radiopharmaceuticals for bones.Uehara T, Jin ZL, Ogawa K, Akizawa H, Hashimoto K, Nakayama M, Arano Y. Nucl Med Biol. 2007 Jan; 34(1):79-87. Epub 2006 Nov 16.
- Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals.[Bioconjug Chem. 2005]Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals.Ogawa K, Mukai T, Arano Y, Ono M, Hanaoka H, Ishino S, Hashimoto K, Nishimura H, Saji H. Bioconjug Chem. 2005 Jul-Aug; 16(4):751-7.
- Systemic radionuclide therapy in pain palliation.[Am J Hosp Palliat Care. 2005]Systemic radionuclide therapy in pain palliation.Liepe K, Runge R, Kotzerke J. Am J Hosp Palliat Care. 2005 Nov-Dec; 22(6):457-64.
- Review Strontium Chloride Sr 89.[Drugs and Lactation Database (...]Review Strontium Chloride Sr 89.. Drugs and Lactation Database (LactMed®). 2006
- Rhenium-186 HEDP - Drugs and Lactation Database (LactMed®)Rhenium-186 HEDP - Drugs and Lactation Database (LactMed®)
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