Summary of Use during Lactation

Information in this record refers to the use of urea C 14 as a diagnostic agent. No information is available on the use of urea C 14 during breastfeeding. However, administration of urea C 14 directly to pediatric patients is considered to be safe.[1] International guidelines state that breastfeeding need not be interrupted after administration of urea C 14.[2]

Drug Levels

Carbon 14 is a low-energy beta emitter with a physical half-life of about 5730 years.[3]

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Urea C 13

References

1.

Pathak CM, Kaur B, Khanduja KL. 14C-urea breath test is safe for pediatric patients. Nucl Med Commun. 2010;31:830–5. [PubMed: 20864821]

2.

Mattsson S, Johansson L, Leide Svegborn S, et al. Radiation dose to patients from radiopharmaceuticals: A compendium of current information related to frequently used substances. ICRP Publication 128. Annex D. Recommendations on breast-feeding interruptions. Ann ICRP. 2015;44(2) Suppl:319–21. [PubMed: 26069086]

3.

Leide-Svegborn S, Ahlgren L, Johansson L, et al. Excretion of radionuclides in human breast milk after nuclear medicine examinations. Biokinetic and dosimetric data and recommendations on breastfeeding interruption. Eur J Nucl Med Mol Imaging. 2016;43:808–21. [PubMed: 26732471]

Substance Name

Urea C 14

CAS Registry Number

594-05-8

Drug Class

Breast Feeding

Lactation

Radiopharmaceuticals

Carbon Radioisotopes

Urea

Diagnostic Agents