Leflunomide

Publication Details

Estimated reading time: 1 minute

CASRN: 75706-12-6

image 135012014 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the use of leflunomide during breastfeeding, so an alternate drug is preferred, especially while nursing a newborn or preterm infant[1-3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Flint J, Panchal S, Hurrell A, et al. BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding-Part I: Standard and biologic disease modifying anti-rheumatic drugs and corticosteroids. Rheumatology (Oxford). 2016;55:1693–7. [PubMed: 26750124]
2.
Sammaritano LR, Bermas BL, Chakravarty EE, et al. 2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases. Arthritis Rheumatol. 2020;72:529–56. [PubMed: 32090480]
3.
Russell MD, Dey M, Flint J, et al. British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: Immunomodulatory anti-rheumatic drugs and corticosteroids. Rheumatology (Oxford). 2023;62:e48–e88. [PMC free article: PMC10070073] [PubMed: 36318966]

Substance Identification

Substance Name

Leflunomide

CAS Registry Number

75706-12-6

Drug Class

Breast Feeding

Lactation

Milk, Human

Antirheumatic Agents

Immunosuppressive Agents

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