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Probe Reports from the NIH Molecular Libraries Program [Internet].
Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Table of contents
ML265: A potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model.
Jiang J, Walsh MJ, Brimacombe KR, et al. 2012 Mar 16 [Updated 2013 May 8].
Discovery of ML370, an inhibitor of Vibrio cholerae Quorum Sensing Acting via the LuxO response regulator.
Faloon P, Weiner WS, Matharu DS, et al. 2013 Apr 12 [Updated 2014 Sep 18].
Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase.
Schoenen FJ, Weiner WS, Baillargeon P, et al. 2013 Apr 12 [Updated 2014 Sep 18].
Hepatitis C Virus NS3 Helicase Inhibitor Discovery.
Li K, Frankowski KJ, Hanson AM, et al. 2011 Dec 16 [Updated 2013 Mar 14].
Probe Development Efforts for an Allosteric Agonist of the Sphingosine 1-phosphate Receptor 3 (S1P3).
Guerrero M, Poddutoori R, Pinacho-Crisostomo F, et al. 2011 Aug 31 [Updated 2013 Feb 25].
Optimization and characterization of a triazole urea inhibitor for platelet-activating factor acetylhydrolase type 2 (PAFAH2).
Adibekian A, Hsu KL, Speers AE, et al. 2011 Mar 31 [Updated 2013 Mar 7].
Discovery of a Small Molecule Activator of the Hypoxia Inducible Factor Pathway.
Theriault JR, Perez J, Gilbert S, et al. 2011 Mar 31 [Updated 2013 Mar 14].
Scaffold Hopping Affords a Highly Selective in vitro and in vivo T-Type Calcium Inhibitor Probe Free From IP Issues.
Xie X, Brogan JT, Schulte ML, et al. 2011 Mar 31 [Updated 2013 Mar 22].
ML223: A Small Molecule Probe With In Vivo Activity Against Acute Myeloid Leukemia Subtype M4Eo.
Marugan JJ, Xiao J, Zheng W, et al. 2011 Apr 4 [Updated 2013 Feb 28].
Identification of a Selective Small-Molecule Inhibitor of Breast Cancer Stem Cells - Probe 1.
Carmody L, Germain A, Morgan B, et al. 2011 Apr 15 [Updated 2013 Feb 28].
A Small Molecule Inhibitor of Scavenger Receptor BI-mediated Lipid Uptake—Probe 1.
Faloon PW, Dockendorff C, Youngsaye W, et al. 2011 Dec 15 [Updated 2014 Sep 18].
Discovery of Potent and Highly Selective Inhibitors of GSK3b.
An WF, Germain AR, Bishop JA, et al. 2012 Apr 16 [Updated 2014 May 13].
Optimization and characterization of triazole urea inhibitors for abhydrolase domain containing protein 6 (ABHD6).
Hsu KL, Tsuboi K, Speers AE, et al. 2012 Apr 12 [Updated 2013 Mar 14].
Optimization and characterization of a carbamate inhibitor for plasma platelet-activating factor acetylhydrolase (pPAFAH).
Nagano JMG, Hsu KL, Speers AE, et al. 2011 Nov 30 [Updated 2014 May 13].
Discovery of Inverse Agonists for the Liver Receptor Homologue-1 (LRH1; NR5A2).
Busby S, Nuhant P, Cameron M, et al. 2010 Oct 12 [Updated 2011 Dec 12].
Optimization and Characterization of an Inhibitor for NADPH Oxidase 1 (NOX-1).
Gianni D, Nicolas N, Zhang H, et al. 2010 Oct 13 [Updated 2011 Dec 12].
Discovery of Inhibitors of Anti-Apoptotic Protein A1.
Bittker JA, Weiwer M, Wei G, et al. 2011 Mar 21 [Updated 2011 Nov 21].
Identification of Small Molecules that Selectively Inhibit Fluconazole-Resistant Candida Albicans in the Presence of Fluconazole but not in its Absence - Probe 3.
Hartland CL, Youngsaye W, Dockendorff C, et al. 2011 Mar 31 [Updated 2011 Nov 21].
Screen for RAS-Selective Lethal Compounds and VDAC Ligands - Probe 2.
Bittker JA, Weiwer M, Lewis T, et al. 2011 Feb 10 [Updated 2011 Dec 12].
Campaign to Identify Agonists of Transient Receptor Potential Channels 3 and 2 (TRPML3 & TRPML2).
Saldanha SA, Grimm C, Mercer BA, et al. 2009 Nov 13 [Updated 2011 May 5].
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