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com in Drosophila melanogasterNeurospora crassa OR74AEscherichia phage D108All 6 Gene records
Probe Reports from the NIH Molecular Libraries Program [Internet].
Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Table of contents
A small molecule inhibitor of Caspase 1.
Boxer MB, Shen M, Auld DS, et al. 2010 Feb 25 [Updated 2011 Mar 3].
Identification of selective inhibitors of cdc2-like kinases 1 and 4 (Clk1, Clk4).
Coombs TC, Tanega C, Shen M, et al. 2012 Apr 16 [Updated 2013 May 8].
Discovery of ML323 as a Novel Inhibitor of the USP1/UAF1 Deubiquitinase Complex.
Dexheimer TS, Rosenthal AS, Liang Q, et al. 2012 Oct 23 [Updated 2014 Sep 18].
Discovery, SAR and Biological Evaluation of Aryl-thiazol-piperidines as SMN Modulators.
Xiao J, Marugan JJ, Zheng W, et al. 2010 Mar 19 [Updated 2011 May 5].
Potent and selective inhibitors of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD).
Jadhav A, Niesen FH, Schultz L, et al. 2010 Mar 4 [Updated 2011 Mar 11].
Potent inhibitors of lipid droplet formation.
Zou J, Ganji S, Pass I, et al. 2011 Oct 31 [Updated 2014 May 13].
A Potent and Selective Inhibitor of Cdc42 GTPase.
Surviladze Z, Waller A, Strouse JJ, et al. 2010 Feb 27 [Updated 2010 Dec 16].
Small Molecules Targeting the Mitochondrial Permeability Transition.
Sileikyte J, Roy S, Porubsky P, et al. 2014 Apr 15 [Updated 2015 Jan 16].
Three small molecule pan activator families of Ras-related GTPases.
Surviladze Z, Ursu O, Miscioscia F, et al. 2009 May 18 [Updated 2010 Sep 2].
Discovery of a potent, selective and in vivo active mGluR4 positive allosteric modulator.
Hopkins CR, Niswender CM, Lewis LM, et al. 2009 Dec 18 [Updated 2010 Oct 20].
Scaffold Hopping Affords a Highly Selective in vitro and in vivo T-Type Calcium Inhibitor Probe Free From IP Issues.
Xie X, Brogan JT, Schulte ML, et al. 2011 Mar 31 [Updated 2013 Mar 22].
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator (PAM).
Lewis LM, Bridges TM, Niswender CM, et al. 2009 Sep 1 [Updated 2010 Oct 20].
Small-Molecule Inhibitors of Vaccinia-H1-Related Phosphatase VHR.
Tautz L, Mustelin T, Wu S, et al. 2009 Oct 31 [Updated 2010 Oct 4].
Discovery of a small molecule inhibitor of ROMK with unprecedented selectivity.
Denton JS, Weaver CD, Chauder BA, et al. 2009 Sep 1 [Updated 2010 Oct 20].
Discovery and development of a second highly selective M1 Positive Allosteric Modulator (PAM).
Bridges TM, Reid PR, Lewis LM, et al. 2010 Mar 31 [Updated 2010 Oct 29].
An inhibitor of the Cdc2-like kinase 4 (Clk4).
Rosenthal AS, Tanega C, Shen M, et al. 2010 Mar 29 [Updated 2011 Mar 3].
HTS for Identification of Inhibitors against the ERK Signaling Pathway using a Homogenous Cell-based Assay.
Marugan J, Dehdashti S, Zheng W, et al. 2009 May 18 [Updated 2010 Sep 2].
Selective small molecule activator of the apoptotic arm of the UPR.
Flaherty DP, Golden JE, Liu C, et al. 2012 Apr 1 [Updated 2013 Feb 28].
Discovery of a novel metabotropic glutamate receptor 4 (mGlu4) positive allosteric modulator (PAM) extended probe: Characterization of ML292, a potent and selective mGlu4 PAM which produces efficacy alone or in combination with L-DOPA in preclinical rodent models of Parkinson's disease.
Engers DW, Jones CK, Bubser M, et al. 2012 Apr 2 [Updated 2013 Feb 25].
SMN Modulator ML372 Increases SMN Protein Abundance, Body Weight, Lifespan, and Rescues Motor Function in SMNΔ7 SMA Mice.
Burnett BG, Xiao J, Southall N, et al. 2013 Dec 15 [Updated 2015 Feb 11].
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