Case Finding, Diagnosis and Follow-Up of Patients with Affective Disorders
Summary and conclusions
SBU Yellow Report No. 212
Swedish Council on Health Technology Assessment
October 2012
Aims
To evaluate the sensitivity and specificity of instruments used to screen, diagnose and grade the severity of depression.
To assess whether instruments improves the treatment outcome for patients with depression or bipolar disorder.
Results
Two diagnostic interviews, SCID-I and MINI, have high sensitivity and specificity for depression and mania in adults. PRIME-MD has a low sensitivity (<70 %).
Some instruments for screening have adequate sensitivity (specificity was of less concern): CBCL and BDI-I (depression) and YMRS and GBI (mania) children and adolescents; BDI-II (depression) and HCL-32 and MDQ (mania) for adults and GDS 15 and GDS 30 for elderly. HADS and PHQ-9 are not adequate.
The evidence for all severity grading instruments was insufficient. Screening as part of an enhanced management of depression improves recovery and improvement for adult patients in primary care but the effect is small.
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Copyright © 2012 by the Swedish Council on Health Technology Assessment. All content unless otherwise noted is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Bookshelf ID: NBK448027, PMID: 28876779
