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Wilt TJ, Shaukat A, Shamliyan T, et al. Lactose Intolerance and Health. Rockville (MD): Agency for Healthcare Research and Quality (US); 2010 Feb. (Evidence Reports/Technology Assessments, No. 192.)

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

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Lactose Intolerance and Health.

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Appendix Table D2Association between low dairy Ca++ intake and bone fractures

StudyComparisonOutcomeEstimateMean (95% CI)
Goulding, 200437
Country: New Zealand Prepubertal children with a history of long-term milk avoidance Ca++ intake difference in comparison groups: NR/NR
Calcium intake below 300 mg/day vs. >300mg/dayHistory of fractureCrude OR1.26 (0.34; 4.65)
Looker, 199343
Country: USA
Men and postmenopausal women Ca++ intake difference in comparison groups: NR/Y
Selected calcium cut points (mg~day) <400 vs. >1,000 in menHistory of fractureAdjusted for alcohol use, smoking, physical activity, BMI, and postmenopausal hormone use in the total sample of women in addition to age RR0.51 (0.20; 1.10)
Selected calcium cut points (mg~day) <400 vs. >1,000 in women0.91 (0.50; 1.60)
Selected calcium cut points (mg~day) <400 vs., >1,000 in late menopausal women0.73 (0.30; 1.60)
Tavani, 199549
Country: Italy
Postmenopausal women Ca++ intake difference in comparison groups: NR/NR
Ca++ intake >1,026mg/day vs. <443mg/dayHip fractureAdjusted for age, education, smoking status, total alcohol consumption, and estrogen replacement therapy OR1.20 (0.80; 2.00)

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