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Henriksen K, Battles JB, Keyes MA, et al., editors. Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 2: Culture and Redesign). Rockville (MD): Agency for Healthcare Research and Quality (US); 2008 Aug.

Cover of Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 2: Culture and Redesign)

Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 2: Culture and Redesign).

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Table 1Risk priority number (RPN) scores for components of the paper-based system for ordering, dispensing, and administering chemotherapy that exceeded 150a

ProcessComponent that warranted additional concernRPN score
OrderingGenerating an “OK to give” order by a chemotherapy-certified physician, who did not obtain and review all required information. This requires a nononcologist provider to hold the order until the last piece of pertinent clinical data is available before transmitting the order to receiving departments (i.e., a conditional “OK to give” order).360
DispensingNot recognizing that orders were transmitted with the incorrect patient name420
A problem with legibility associated with either handwriting or fax transmission280
An incorrect volume of diluent being used for reconstitution of a medication product200
A medication being injected into the incorrect admixture bag, if multiple products were being prepared at the same time224
AdministrationInfusion center nursing staff not recognizing premedications that were indicated but not ordered based upon previous adverse drug reactions210
The second infusion center nurse failing to check multiple patient identifiers210
The second infusion center nurse performing the required checks without recognizing an error210
The second infusion center nurse administering a medication by an incorrect route of administration200
The second infusion center nurse failing to provide patient followup210
a

A predetermined level deemed to warrant additional analysis.

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