This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments.

The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.

Contents

• Introduction
• Acknowledgements
• List of Contributors
• Hippocampal Mechanisms for the Segmentation of Space by Goals and Boundaries
  Sam McKenzie and György Buzsáki.
  Published online: May 3, 2016.
  • Introduction
  • Goals and Other Boundaries Anchor and Alter the Hippocampal Place Code
  • The Hippocampus Organizes the Spatial Code into Temporal Sequences
  • Theta Sequences Code for Behaviorally Relevant Spatial Segments
  • How Could Theta Sequences Be Integrated by Post-synaptic Readers?
  • Conclusion
  • Acknowledgments
  • References
• Cortical Evolution: Introduction to the Reptilian Cortex
  Gilles Laurent, Julien Fournier, Mike Hemberger, Christian Müller, Robert Naumann, Janie M. Ondracek, Lorenz Pammer, Samuel Reiter, Mark Shein-Idelson, Maria Antonietta Tosches, and Tracy Yamawaki.
  Published online: May 3, 2016.
  • Reptilian Brain Structure and Evolution
  • Basic Architecture and Functional Features
  • Physiological Adaptations of the Reptilian Brain
  • Brain and Behavior
  • References
• Flow of Information Underlying a Tactile Decision in Mice
  Nuo Li, Zengcai V. Guo, Tsai-Wen Chen, and Karel Svoboda.
  Published online: May 3, 2016.
  • Introduction
  • Head-Fixed Tactile Decision Behavior and Involved Cortical Regions
  • Premotor Dynamics Underlying Motor Planning
  • Open Questions
  • Acknowledgment
  • References
• The Visual Brain: Computing Through Multiscale Complexity
  Yves Frégnac, Julien Fournier, Florian Gérard-Mercier, Cyril Monier, Marc Pananceau, Pedro Carelli, and Xoana Troncoso.
  Published online: May 3, 2016.
  • Introduction
  • The Synaptic Imprint of Mesoscopic “Immergence” in Visual RFs
  • Synaptic Correlates of Perceptual Gestalt Laws in the “Silent Surround” of V1 RFs
  • Conclusion
  • Acknowledgments
  • References
• Grid Cells and Spatial Maps in Entorhinal Cortex and Hippocampus
  Tor Stensola and Edvard I. Moser.
  Published online: May 3, 2016.
  • Place Cells and Grid Cells
  • Discretization of the Entorhinal Grid Map
  • Combinatorics in Grid Cells and Remapping in Place Cells
  • Topography in Parahippocampal Systems
  • Mechanisms of Grid Spacing
  • Shearing-Induced Asymmetries in Grid Cells
  • Oblique Effect in Grids?
  • Conclusions
  • References
• The Striatum and Decision-Making Based on Value
  Ann M. Graybiel.
  Published online: May 3, 2016.
  • References
• Decoding the Dynamics of Conscious Perception: The Temporal Generalization Method
  Stanislas Dehaene and Jean-Rémi King.
  Published online: May 3, 2016.
  • The Temporal Generalization Method
  • Advantages of Multivariate Decoding Methods
  • A Test Using Auditory Novelty Signals
  • Late Metastable Activity as a Signature of Consciousness
  • Conclusion
  • References
• Sleep and Synaptic Down-Selection
  Giulio Tononi and Chiara Cirelli.
  Published online: May 3, 2016.
  • Sleep Is Universal and Probably Essential, But Why?
  • Sleep Helps Memory Consolidation, Gist Extraction, and Integration
  • Sleep Helps Memory, But How? Is It Replay or Synaptic Down-Selection?
  • Synapses Get Stronger in Wake and Weaker in Sleep
  • SHY: The Price of Plasticity
  • Acknowledgements
  • References
• Psyche, Signals and Systems
  Costas A. Anastassiou and Adam S. Shai.
  Published online: May 3, 2016.
  • Introduction
  • Signals of Conscious Perception
  • Biophysical Foundations of Signals Associated with Conscious Perception
  • From Cellular Biophysics to Systems and Computations Associated with Conscious Perception
  • Acknowledgments
  • References
• Federating and Integrating What We Know About the Brain at All Scales: Computer Science Meets the Clinical Neurosciences
  Richard Frackowiak, Anastasia Ailamaki, and Ferath Kherif.
  Published online: May 3, 2016.
  • Introduction
  • Syndromic Diagnosis
  • A Theory of the Brain
  • Computers
  • Data and Data Mining
  • Simulating the Brain
  • Data Provenance
  • Disease Signatures
  • Human Brain Project
  • Clinical Neuroscience-Related Big Data Initiatives
  • Changing the Culture
  • Acknowledgments
  • References