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Thomson RG, De Brún A, Flynn D, et al. Factors that influence variation in clinical decision-making about thrombolysis in the treatment of acute ischaemic stroke: results of a discrete choice experiment. Southampton (UK): NIHR Journals Library; 2017 Jan. (Health Services and Delivery Research, No. 5.4.)

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Factors that influence variation in clinical decision-making about thrombolysis in the treatment of acute ischaemic stroke: results of a discrete choice experiment.

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Appendix 5Factor analysis of Institutional Culture Scale

Factor analysis using principal component analysis (PCA) with orthogonal rotation (varimax) was conducted on the six-item scale. The Kaiser–Meyer–Olkin (KMO) measure verified the sampling adequacy for the analysis, KMO = 0.83, which suggests that the sample size is adequate for factor analysis.132 Bartlett’s test of sphericity [χ2(15) = 338.95; p < 0.001] indicated that correlations between items were sufficiently large for PCA. An initial analysis was run to obtain eigenvalues for each component in the data. The results indicated that only one component had an eigenvalue of > 1 and explained 57.47% of the variance. Following inspection of the scree plot, the one component was confirmed and retained for the final analysis. Table 16 displays the factor loadings after varimax rotation. Factor loadings of > 0.55 are considered ‘good’ to ‘excellent’.133 The one-component solution suggests that the items on the scale all measure institutional culture of thrombolysis. Reliability analysis was conducted and internal consistency was high, with Cronbach’s alpha of 0.84.

TABLE 16

TABLE 16

Rotated factor loadings for Institutional Culture Scale

Copyright © Queen’s Printer and Controller of HMSO 2017. This work was produced by Thomson et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

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