FIGURE 9. Cumulative hazard of developing breast cancer in 480 BRCA1 mutation carriers, by risk group (overall breast cancer risk score split into quintiles), based on the 18 SNPs from Turnbull et al.

FIGURE 9

Cumulative hazard of developing breast cancer in 480 BRCA1 mutation carriers, by risk group (overall breast cancer risk score split into quintiles), based on the 18 SNPs from Turnbull et al.131 Source: reproduced with permission from Ingham SL, Warwick J, Byers H, Lalloo F, Newman WG, Evans DGR. Is multiple SNP testing in BRCA2 and BRCA1 female carriers ready for use in clinical practice? Results from a large Genetic Centre in the UK. Clinical Genetics 2013, 84:1, 37–42, © 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.140

From: Chapter 3, Project 2: assessment of predictive value of new genetic variants

Cover of Improvement in risk prediction, early detection and prevention of breast cancer in the NHS Breast Screening Programme and family history clinics: a dual cohort study
Improvement in risk prediction, early detection and prevention of breast cancer in the NHS Breast Screening Programme and family history clinics: a dual cohort study.
Programme Grants for Applied Research, No. 4.11.
Evans DG, Astley S, Stavrinos P, et al.
Southampton (UK): NIHR Journals Library; 2016 Aug.
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